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A4673

Albendazole

Name: Albendazole
Brand: SIAL

analytical standard, ≥98%

Sinónimos:

Methyl 5-(propylthio)-2-benzimidazolecarbamate

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Fórmula empírica (notación de Hill):

C₁₂H₁₅N₃O₂S

Número CAS:

54965-21-8

Peso molecular:

265.33

NACRES:

NA.24

PubChem Substance ID:

329770859

UNSPSC Code:

41116107

EC Number:

259-414-7

MDL number:

MFCD00083232

Servicio técnico

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Propiedades

grade

analytical standard

Quality Segment

100

assay

≥98%

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CCCSc1ccc2[nH]c(NC(=O)OC)nc2c1

InChI

1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

InChI key

HXHWSAZORRCQMX-UHFFFAOYSA-N

Descripción

General description

Chemical structure: benzimidazole

Albendazole is a benzimidazole derivative used for the treatment of human gastrointestinal helmintiasis. It inhibits microtubule and blocks the glucose uptake that causes depletion of glycogen stores and lowering formation of adinosine triphosphate (ATP) in the larval and adult stages of susceptible parasite.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Albendazole may be used as a reference standard for the determination of albendazole and its major metabolites, albendazole sulphoxide and albendazole sulphone by high-performance liquid chromatography (HPLC) method in mice plasma.

Biochem/physiol Actions

Binds to tubulin and inhibits microtubule assembly.

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pictograms

GHS08,GHS09

signalword

Warning

hcodes

H361d,H373,H410

pcodes

P202 - P260 - P273 - P280 - P308 + P313 - P391

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Oral

target_organs

Adrenal gland,Blood,male reproductive organs,spleen

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c