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Merck

G5767

D-(+)-Glucosa

ACS reagent

Sinónimos:

Dextrosa

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About This Item

Fórmula empírica (notación de Hill):
C6H12O6
Número CAS:
50-99-7
Peso molecular:
180.16
PubChem Substance ID:
24895228
UNSPSC Code:
12352201
MDL number:
MFCD00063774
NACRES:
NA.21
EC Number:
200-075-1
Beilstein/REAXYS Number:
1724615

Nombre del producto

D-(+)-Glucosa, ACS reagent

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

InChI key

WQZGKKKJIJFFOK-DVKNGEFBSA-N

SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

biological source

wheat

grade

ACS reagent

form

powder

optical activity

[α]25/D +52.5 to +53.0°(lit.)

impurities

Starch, passes test
≤0.002 meq/g Titratable acid
≤0.005% Insoluble matter

ign. residue

≤0.02%

loss

≤0.2% loss on drying, 105°C

color

colorless

mp

150-152 °C (lit.)

anion traces

chloride (Cl-): ≤0.01%
sulfate, sulfite (as SO42-): ≤0.005%

cation traces

Fe: ≤5 ppm
heavy metals: ≤5 ppm (by ICP-OES)

storage temp.

room temp

Quality Level

200

Gene Information

human ... PYGM(5837)

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Application

D-(+)-Glucose has been used:
  • as a supplement in Dulbecco′s phosphate-buffered saline (DPBS) for standardized serum bactericidal assay (SBA) using human complement
  • as a component in 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES)-buffered Tyrode′s solution to treat the excised diaphragmatic specimens to assess the effect of osmolarity changes on the intrinsic lymphatic pumping mechanism
  • to study the effect of restoring circulating glucose content in insulin-responsive neurons of rats
  • for oral glucose tolerance tests (OGTTs)

Biochem/physiol Actions

Glucose, the universal energy source for all human cells, is the vital precursor for the production and conversion of several downstream carbohydrates. The uptake of glucose is a key indicator of cellular energy metabolism. Glucose infusion can block the release of oxytocin and vasopressin by insulin-induced hypoglycemia in humans.

General description

D-glucose, an aldohexose, possesses four chiral carbon atoms. It is an important product obtained from starch hydrolyzed by acid and/or enzymes.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Preparation Note

The material may produce a yellowish solution if prepared at a higher concentration than 2 g + 15mL.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000519495
0000519495
BCCP0321
0000511126
0000511126

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Biochemical pharmacology, 92(2), 380-388 (2014-09-10)
Skeletal muscle accounts for ∼ 80% of postprandial glucose clearance, and skeletal muscle glucose clearance is crucial for maintaining insulin sensitivity and euglycemia. Insulin-stimulated glucose clearance/uptake entails recruitment of glucose transporter 4 (GLUT4) to the plasma membrane (PM) in a
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Yu-ting Alex Chiang et al.
American journal of physiology. Endocrinology and metabolism, 306(7), E707-E722 (2013-12-26)
p21-Activated protein kinases (PAKs) are centrally involved in a plethora of cellular processes and functions. Their function as effectors of small GTPases Rac1 and Cdc42 has been extensively studied during the past two decades, particularly in the realms of cell
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