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PHR1289

Enalapril Maleate

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

Enalapril maleate salt, (S)-N-[1-(Ethoxycarbonyl)-3-phenylpropyl]-Ala-Pro maleate salt

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Fórmula empírica (notación de Hill):
C20H28N2O5 · C4H4O4
Número CAS:
76095-16-4
Peso molecular:
492.52
NACRES:
NA.24
UNSPSC Code:
41116107
EC Number:
278-375-7
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Quality Segment

300

grade

certified reference material, pharmaceutical secondary standard

agency

USP 1235300, traceable to Ph. Eur. E0109000

API family

enalapril

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

C[C@@H](C(N1[C@H](C(O)=O)CCC1)=O)N[C@H](CC(OCC)=O)CCC2=CC=CC=C2.O=C(OO)/C=C\C(O)=O

InChI

1S/C21H30N2O5.C4H4O5/c1-3-28-19(24)14-17(12-11-16-8-5-4-6-9-16)22-15(2)20(25)23-13-7-10-18(23)21(26)27;5-3(6)1-2-4(7)9-8/h4-6,8-9,15,17-18,22H,3,7,10-14H2,1-2H3,(H,26,27);1-2,8H,(H,5,6)/b;2-1-/t15-,17-,18-;/m0./s1

InChI key

UQKQUZOIQFOJOI-KJHLASMFSA-N

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Enalapril Maleate is a drug, which is widely used as an antihypertensive and a vasodilator in congestive heart failure. It is a derivative of 2 amino acids such as L-alanine and L-proline.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Enalapril Maleate may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using derivative UV spectrophotometry and chromatography techniques.

Biochem/physiol Actions

A long-acting angiotensin-converting enzyme inhibitor.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC3898 in the slot below. This is an example certificate only and may not be the lot that you receive.

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pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H361fd

Hazard Classifications

Repr. 2

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 2

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