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PHR1796

Imipenem

Name: Imipenem
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

Imipenem monohydrate, (5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid monohydrate, Primaxin monohydrate, Tienam monohydrate

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Fórmula empírica (notación de Hill):

C₁₂H₁₇N₃O₄S · H₂O

Número CAS:

74431-23-5

Peso molecular:

317.36

NACRES:

NA.24

PubChem Substance ID:

329823620

UNSPSC Code:

41116107

EC Number:

264-734-5

MDL number:

MFCD09753321

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Propiedades

Quality Segment

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. I0090000, traceable to USP 1337809

API family

imipenem

form

solid

CofA

current certificate can be downloaded

packaging

pkg of 200 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

storage temp.

-10 to -25°C

SMILES string

O.C[C@@H](O)[C@@H]1[C@H]2CC(SCCNC=N)=C(N2C1=O)C(O)=O

InChI

1S/C12H17N3O4S.H2O/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17;/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19);1H2/t6-,7-,9-;/m1./s1

InChI key

GSOSVVULSKVSLQ-JJVRHELESA-N

Descripción

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Imipenem belongs to the class of carbapenems, a beta-lactam antibiotic, effective against aerobic and anaerobic bacteria. Carbapenems act by inhibiting the peptidoglycan synthesis involved in bacterial cell wall formation, thus causing the death of the target microorganism.

Application

Imipenem may be used as a pharmaceutical reference standard for the quantification of the analyte in biological samples and pharmaceutical formulations by various analytical techniques.

Biochem/physiol Actions

Imipenem monohydrate is a broad spectrum B-lactam antibiotic. It is a member of the carbapenem class of "magic bullet" antibiotics for severe infections.

Imipenem monohydrate is a broad spectrum B-lactam antibiotic.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC0262 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c