A5222
D-Amino Acid Oxidase from porcine kidney
powder, ≥1.5 units/mg solid
Sinónimos:
D-AAO, D-Amino acid: oxygen oxidoreductase (deaminating)
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Número CAS:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-563-5
MDL number:
Specific activity:
≥1.5 units/mg solid
Servicio técnico
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D-amino acid oxidase (DAO) is a potential target molecule for the treatment of chronic pain and schizophrenia . D-amino acid oxidase is used to oxidize D-amino acids to their corresponding imino acids.
Other Notes
One unit will oxidatively deaminate 1.0 μmole of D-alanine to pyruvate per minute at pH 8.3 at 25 °C, in the presence of a catalase.
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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Cindy J Lee et al.
Metabolites, 12(9) (2022-09-24)
The pancreatic islets of Langerhans are clusters of cells that function as endocrine units synthesizing and releasing insulin and a range of additional peptide hormones. The structural and chemical characteristics of islets change during type 2 diabetes development. Although a
Seth C Hopkins et al.
The Journal of pharmacology and experimental therapeutics, 345(3), 502-511 (2013-03-23)
Inhibition of d-amino acid oxidase (DAAO) activity is a potential target for the treatment of chronic pain. Here we characterized the effects of systemic administration of the DAAO inhibitor 4H-furo[3,2-b]pyrrole-5-carboxylic acid (SUN) in rat models of neuropathic and inflammatory pain.
Glutamine 89 is a key residue in the allosteric modulation of human serine racemase activity by ATP.
Andrea V Canosa et al.
Scientific reports, 8(1), 9016-9016 (2018-06-15)
Serine racemase (SR) catalyses two reactions: the reversible racemisation of L-serine and the irreversible dehydration of L- and D-serine to pyruvate and ammonia. SRs are evolutionarily related to serine dehydratases (SDH) and degradative threonine deaminases (TdcB). Most SRs and TdcBs