C1426
Cesium methanesulfonate
used in patch clamp techniques
Sinónimos:
CsMSF, CsMeS, Methanesulfonic acid cesium salt
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Fórmula lineal:
CH3O3SCs
Número CAS:
Peso molecular:
228.00
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12161700
MDL number:
Form:
powder
Servicio técnico
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Permítanos ayudarleQuality Level
form
powder
mp
262-264 °C (lit.)
SMILES string
[Cs+].CS([O-])(=O)=O
InChI
1S/CH4O3S.Cs/c1-5(2,3)4;/h1H3,(H,2,3,4);/q;+1/p-1
InChI key
DJKJXRLREATOMF-UHFFFAOYSA-M
General description
Cesium methanesulfonate is used as a component of intracellular recording solutions of electrodes for patch clamp techniques in cell electrophysiology studies. Cesium methanesulfonate is used as an current carrier as cesium acts as a potassium (K+) channel blocker, while methanesulfonate is not transported through chloride (Cl-) channels.
Application
Cesium methanesulfonate has been used as a supplement in intracellular solution for the patch clamp recording system.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Diverse voltage-sensitive dyes modulate GABAA receptor function.
Mennerick., S., et al.
The Journal of Neuroscience, 24, 2871-2879 (2010)
An optogenetics- and imaging-assisted simultaneous multiple patch-clamp recording system for decoding complex neural circuits.
Wang G
Nature Protocols, 10, 397-397 (2015)
L Zhang et al.
Pflugers Archiv : European journal of physiology, 426(3-4), 247-253 (1994-02-01)
Using the whole-cell recording technique, we have examined the slow Ca(2+)-activated afterhyperpolarization (AHP) and its underlying current (IAHP) in hippocampal CA1 neurones of brain slices obtained from mature rats. Specifically we have studied the effects of the anion component of