L8000
L-Leucine
≥98% (HPLC), suitable for ligand binding assays
Sinónimos:
(S)-2-Amino-4-methylpentanoic acid
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Fórmula lineal:
(CH3)2CHCH2CH(NH2)CO2H
Número CAS:
Peso molecular:
131.17
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-522-0
MDL number:
Beilstein/REAXYS Number:
1721722
Servicio técnico
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Permítanos ayudarleNombre del producto
L-Leucine, reagent grade, ≥98% (HPLC)
grade
reagent grade
Quality Level
assay
≥98% (HPLC)
form
powder
technique(s)
ligand binding assay: suitable
impurities
isoleucine and methionine, essentially free
color
white to off-white
mp
>300 °C (lit.)
application(s)
peptide synthesis
SMILES string
CC(C)C[C@H](N)C(O)=O
InChI
1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
InChI key
ROHFNLRQFUQHCH-YFKPBYRVSA-N
Application
L-Leucine has been used as an agonist of mechanistic target of rapamycin (mTOR) to determine whether AMPK/mTOR pathway is involved in berberine-mediated autophagy in J774A.1 cells. It has also been used for the selection of transformed cells.
Biochem/physiol Actions
Leucine is a non-glucogenic, essential amino acid. It is a branched-chain amino acid that is a structural component of proteins. Leucine positively influences insulin release to eliminate toxic sugars out of the blood. The degradation of leucine leads to the formation of ketone bodies.
Clase de almacenamiento
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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