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Merck

T0625

Taurine

≥99%

Sinónimos:

2-Aminoethanesulfonic acid

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About This Item

Fórmula lineal:
NH2CH2CH2SO3H
Número CAS:
Peso molecular:
125.15
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
203-483-8
MDL number:
Beilstein/REAXYS Number:
1751215

Nombre del producto

Taurine, ≥99%

InChI key

XOAAWQZATWQOTB-UHFFFAOYSA-N

InChI

1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)

SMILES string

NCCS(O)(=O)=O

biological source

synthetic

assay

≥99%

form

powder

color

white

mp

>300 °C (lit.)

application(s)

cell analysis

storage temp.

room temp

Quality Level

Gene Information

human ... GRIN1(2902)
rat ... Ppm1a(24666)

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Application

Taurine has been used for the isolation and growth of taurine-utilizing purple non-sulfur bacteria and in phototrophic growth experiments.

Biochem/physiol Actions

Non-selective endogenous agonist at glycine receptors.
Non-selective endogenous agonist at glycine receptors. Conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism.
Taurine modulates the concentration of intracellular calcium, protects against ischemia-reperfusion injury and possesses blood pressure-lowering properties. It also has a role in bile formation and fat digestion. Deficiency of taurine is associated with anxiety, hyperactivity, epilepsy and depression.

General description

Taurine (2-aminoethanesulphonic acid) is predominantly found in the retina and heart and is also found in the brain, intestine, skeletal muscles and kidneys.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Phototrophic utilization of taurine by the purple nonsulfur bacteria Rhodopseudomonas palustris and Rhodobacter sphaeroides.
Novak RT
Microbiology, 150(Pt 6), 1881-1891 (2004)
The potential health benefits of taurine in cardiovascular disease.
Xu YJ
Experimental and Clinical Cardiology, 13(2), 57-65 (2008)
Shozo Sonoda et al.
Nature protocols, 4(5), 662-673 (2009-04-18)
We provide our detailed, standardized in vitro protocol for the culture and differentiation of human retinal pigment epithelial (RPE) cells into a highly polarized and functional monolayer. Disruption of the polarized RPE function plays an important role in the pathogenesis
Felizia K Voss et al.
Science (New York, N.Y.), 344(6184), 634-638 (2014-05-03)
Regulation of cell volume is critical for many cellular and organismal functions, yet the molecular identity of a key player, the volume-regulated anion channel VRAC, has remained unknown. A genome-wide small interfering RNA screen in mammalian cells identified LRRC8A as
Zi-Bing Jin et al.
PloS one, 6(2), e17084-e17084 (2011-02-25)
Retinitis pigmentosa (RP) is the most common inherited human eye disease resulting in night blindness and visual defects. It is well known that the disease is caused by rod photoreceptor degeneration; however, it remains incurable, due to the unavailability of

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