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Merck

X0075000

Xylazine hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

2-(2,6-Dimethylphenylamino)-5,6-dihydro-4H-thiazine hydrochloride, 5,6-Dihydro-2-(2,6-xylidino)-4H-1,3-thiazine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C12H16N2S · HCl
CAS Number:
Molecular Weight:
256.79
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6448471
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grade

pharmaceutical primary standard

API family

xylazine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl[H].Cc1cccc(C)c1NC2=NCCCS2

InChI

1S/C12H16N2S.ClH/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12;/h3,5-6H,4,7-8H2,1-2H3,(H,13,14);1H

InChI key

QYEFBJRXKKSABU-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Xylazine hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

α2-Adrenergic receptor agonist, sedative, muscle relaxant.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.


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wgk

WGK 3

pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable



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Ori Furman et al.
Theriogenology, 82(8), 1165-1172 (2014-09-13)
This study establishes an experimental model for subclinical mastitis induced by Gram-positive (G+) exosecretions of Staphylococcus aureus origin or Gram-negative (G-) endotoxin of Escherichia coli origin to examine its effects on follicular growth and steroid concentrations in Holstein dairy cows.
N Pluchino et al.
Steroids, 95, 104-110 (2015-01-18)
Estetrol (E4), a naturally occurring estrogen produced exclusively by human fetal liver, is currently being evaluated for potential use in contraception and menopausal care in humans. The present study was designed to profile E4 effects on the central nervous system
Javier Gutiérrez-Cuesta et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 39(13), 2974-2988 (2014-06-20)
The repeated cycles of cessation of consumption and relapse remain the major clinical concern in treating drug addiction. The endogenous opioid system is a crucial component of the reward circuit that participates in the adaptive changes leading to relapse in