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Merck

A7631

(+)-Sodium L-ascorbate

crystalline, ≥98%

Synonym(s):

L(+)-Ascorbic acid sodium salt, Vitamin C sodium salt

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About This Item

Empirical Formula (Hill Notation):
C6H7NaO6
CAS Number:
Molecular Weight:
198.11
NACRES:
NA.79
PubChem Substance ID:
eCl@ss:
34058010
UNSPSC Code:
12352205
EC Number:
205-126-1
MDL number:
Beilstein/REAXYS Number:
3767246
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biological source

synthetic

Quality Level

assay

≥98%

form

crystalline

technique(s)

HPLC: suitable

color

white to off-white

mp

220 °C (dec.) (lit.)

SMILES string

[Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]

InChI

1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1

InChI key

PPASLZSBLFJQEF-RXSVEWSESA-M

General description

Ascorbic acid, also known as vitamin C, is a water-soluble vitamin. L-Ascorbic acid is a reducing agent.

Application

(+)-Sodium L-ascorbate has been used:
  • as a component of cutting solution for storing brain slices of rats
  • as a component of patch pipette internal solution for imaging Ca2+ transients evoked by action potential in rat brain slices
  • as a supplement for arterial smooth muscle cell (SMC) cultures to encourage collagen production

Biochem/physiol Actions

Ascorbic acid exhibits anti-oxidant properties. It is a primary substrate for detoxifying hydrogen peroxide. Ascorbic acid is a co-factor for the synthesis of adrenal steroids and catecholamines. L-Ascorbic acid (Vitamin C) is a water soluble molecule used in a wide variety of applications, including cell culture, as a reducing agent that helps reduce oxidative stress. L-Ascorbate can be regenerated by biological systems.

Disclaimer

May darken in storage.


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Storage Class

11 - Combustible Solids

wgk

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)



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Imaging calcium concentration dynamics in small neuronal compartments
Yasuda R, et al.
Science's STKE : Signal Transduction Knowledge Environment, 219, pl5-pl5 (2004)
Exogenous ascorbic acid (vitamin C) increases resistance to salt stress and reduces lipid peroxidation
Shalata A and Neumann P M
Journal of Experimental Botany, 52(364), 2207-2211 (2001)
Vitamin C is an important cofactor for both adrenal cortex and adrenal medulla
Patak P, et al.
Endocrine Research, 30(4), 871-875 (2004)