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About This Item
Empirical Formula (Hill Notation):
C6H7NaO6
CAS Number:
Molecular Weight:
198.11
NACRES:
NA.79
PubChem Substance ID:
eCl@ss:
34058010
UNSPSC Code:
12352205
EC Number:
205-126-1
MDL number:
Beilstein/REAXYS Number:
3767246
biological source
synthetic
Quality Level
assay
≥98%
form
crystalline
technique(s)
HPLC: suitable
color
white to off-white
mp
220 °C (dec.) (lit.)
SMILES string
[Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]
InChI
1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1
InChI key
PPASLZSBLFJQEF-RXSVEWSESA-M
General description
Ascorbic acid, also known as vitamin C, is a water-soluble vitamin. L-Ascorbic acid is a reducing agent.
Application
(+)-Sodium L-ascorbate has been used:
- as a component of cutting solution for storing brain slices of rats
- as a component of patch pipette internal solution for imaging Ca2+ transients evoked by action potential in rat brain slices
- as a supplement for arterial smooth muscle cell (SMC) cultures to encourage collagen production
Biochem/physiol Actions
Ascorbic acid exhibits anti-oxidant properties. It is a primary substrate for detoxifying hydrogen peroxide. Ascorbic acid is a co-factor for the synthesis of adrenal steroids and catecholamines. L-Ascorbic acid (Vitamin C) is a water soluble molecule used in a wide variety of applications, including cell culture, as a reducing agent that helps reduce oxidative stress. L-Ascorbate can be regenerated by biological systems.
Disclaimer
May darken in storage.
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Storage Class
11 - Combustible Solids
wgk
WGK 1
ppe
Eyeshields, Gloves, type N95 (US)
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Imaging calcium concentration dynamics in small neuronal compartments
Yasuda R, et al.
Science's STKE : Signal Transduction Knowledge Environment, 219, pl5-pl5 (2004)
Exogenous ascorbic acid (vitamin C) increases resistance to salt stress and reduces lipid peroxidation
Shalata A and Neumann P M
Journal of Experimental Botany, 52(364), 2207-2211 (2001)
Vitamin C is an important cofactor for both adrenal cortex and adrenal medulla
Patak P, et al.
Endocrine Research, 30(4), 871-875 (2004)