Skip to Content
Merck

47036

Saponin

Molecular Biology, used as non-ionic surfactant

Synonym(s):

Glycosides, Saponins

Sign In to View Organizational & Contract Pricing.

Select a Size

All Photos(1)

About This Item

CAS Number:
8047-15-2
UNSPSC Code:
12161900
NACRES:
NA.25
EC Number:
232-462-6
MDL number:
MFCD00081981

Product Name

Saponin, Molecular Biology, used as non-ionic surfactant

InChI key

MAEBCGDGGATMSC-OSHGGGOQSA-N

InChI

1S/C58H94O27/c1-52(2)29-7-11-55(5)30(8-12-58-31-15-53(3,22-62)13-14-57(31,23-77-58)32(64)16-56(55,58)6)54(29,4)10-9-33(52)82-50-46(85-51-45(40(71)37(68)27(19-61)80-51)84-49-43(74)39(70)36(67)26(18-60)79-49)44(83-48-42(73)38(69)35(66)25(17-59)78-48)28(21-76-50)81-47-41(72)34(65)24(63)20-75-47/h22,24-51,59-61,63-74H,7-21,23H2,1-6H3/t24-,25-,26-,27-,28+,29?,30-,31+,32-,33+,34+,35-,36-,37-,38+,39+,40+,41-,42-,43-,44+,45-,46-,47+,48-,49-,50+,51+,53-,54+,55-,56+,57?,58?/m1/s1

SMILES string

C[C@]1(CCC23COC4([C@H]2C1)CC[C@@H]5[C@]6(CC[C@@H](C(C6CC[C@]5([C@@]4(C[C@H]3O)C)C)(C)C)O[C@H]7[C@@H]([C@H]([C@H](CO7)O[C@H]8[C@@H]([C@H]([C@@H](CO8)O)O)O)O[C@@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)C)C=O

grade

Molecular Biology

mol wt

1000-2000 g/mol

composition

Sapogenin, 8-25%

technique(s)

HPLC: suitable
protein quantification: suitable

CMC

0.001-0.01%

density

1.015-1.020 g/mL at 20 °C (5% in H2O)(lit.)

foreign activity

DNase, RNase, Protease, Phosphatase, none detected

Quality Level

200

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Glycoside used as a nonionic sufactant and adjuvant in vaccine development.
Saponin has been used:
  • in phosphate-buffered saline (PBS) to block cells for immunocytochemistry and confocal microscopy
  • to permeabilize cells for measuring total mitochondrial mass
  • as an internal control to extract saponin Holothuria nobilis Selenka

Biochem/physiol Actions

Saponins are nonionic surfactant that forms oil-in-water emulsions and acts as a protective colloid. They are used for the direct determination of metals in milk by flame atomic absorption spectrophotometry.
Saponins exhibit anti-tumor, antimicrobial, and anti-herbivore activity. They may also play a key role in plant defense. Saponins also possess several pharmaceutical properties, like anti-inflammatory, antifungal, antibacterial, anti-parasitic, and antiviral activities. Saponins can regulate rhizosphere bacteria in the soil.

General description

Saponins are a large family of amphiphilic glycosides of steroids and triterpenes. Saponins are found in many plants and are localized especially in the root, tuber, bark, leaves, seed, and fruit. They are also present in some animals, like sea cucumber.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319,H335

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCM9617
BCCM7262
BCCL0081
BCCM0351
BCCK1316

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Qingkun Liu et al.
Nature immunology, 20(8), 1023-1034 (2019-07-03)
Stroke is a multiphasic process in which initial cerebral ischemia is followed by secondary injury from immune responses to ischemic brain components. Here we demonstrate that peripheral CD11b+CD45+ myeloid cells magnify stroke injury via activation of triggering receptor expressed on
Yixuan Fang et al.
Aging, 11(14), 4910-4922 (2019-07-23)
Autophagy has been well studied in regulating aging; however, the impact of autophagy in one organ on the aging of other organs has not been documented. In this study, we used a mouse model with deletion of an autophagy-essential gene
Patcharaporn Tippayawat et al.
PLoS neglected tropical diseases, 3(4), e407-e407 (2009-04-09)
Infection with the Gram-negative bacterium Burkholderia pseudomallei is an important cause of community-acquired lethal sepsis in endemic regions in southeast Asia and northern Australia and is increasingly reported in other tropical areas. In animal models, production of interferon-gamma (IFN-gamma) is
Sarah Costers et al.
Veterinary research, 40(5), 46-46 (2009-05-19)
The replication of porcine reproductive and respiratory syndrome virus (PRRSV) in lungs and lymphoid tissues of PRRSV-infected pigs is already strongly reduced before the appearance of neutralizing antibodies, indicating that other immune mechanisms are involved in eliminating PRRSV at those
Shumin Tan et al.
PLoS pathogens, 5(5), e1000407-e1000407 (2009-05-05)
Helicobacter pylori (Hp) intimately interacts with the gastric epithelial surface and translocates the virulence factor CagA into host cells in a contact-dependent manner. To study how Hp benefits from interacting with the cell surface, we developed live-cell microscopy methods to
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service