Key Documents

View All Documentation

76904

Vecuronium bromide

Name: Vecuronium bromide
Brand: SIGMA

Synonym(s):

1-[(2β,3α,5α,16β,17β)-3,17-Bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methyl-piperidinium bromide

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₃₄H₅₇BrN₂O₄

CAS Number:

50700-72-6

Molecular Weight:

637.73

UNSPSC Code:

51152000

NACRES:

NA.77

PubChem Substance ID:

329767429

EC Number:

256-723-9

Beilstein/REAXYS Number:

4837308

MDL number:

MFCD00867762

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

biological source

synthetic

Quality Level

100

assay

≥97.0% (TLC)

form

powder or crystals

functional group

carboxylic acid

SMILES string

[Br-].CC(=O)O[C@H]1C[C@@H]2CC[C@@H]3[C@H](CC[C@@]4(C)[C@H]3C[C@@H]([C@@H]4OC(C)=O)[N+]5(C)CCCCC5)[C@@]2(C)C[C@@H]1N6CCCCC6

InChI

1S/C34H57N2O4.BrH/c1-23(37)39-31-20-25-12-13-26-27(34(25,4)22-29(31)35-16-8-6-9-17-35)14-15-33(3)28(26)21-30(32(33)40-24(2)38)36(5)18-10-7-11-19-36;/h25-32H,6-22H2,1-5H3;1H/q+1;/p-1/t25-,26+,27-,28-,29-,30-,31-,32-,33-,34-;/m0./s1

InChI key

VEPSYABRBFXYIB-PWXDFCLTSA-M

Gene Information

human ... CHRNA1(1134), CHRNB1(1140), CHRND(1144), CHRNE(1145), CHRNG(1146)

Description

Biochem/physiol Actions

Vecuronium Bromide is an aminosteroidal neuromuscular blocking agent. It relaxes the skeletal muscle and decreases oxygen consumption during surgery. It competes with acetylcholine and bind to cholinergic receptors at neuromuscular junctions.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Still not finding the right product?

Explore all of our products under Vecuronium bromide

pictograms

GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Potency of nondepolarizing muscle relaxants on muscle-type acetylcholine receptors in denervated mouse skeletal muscle.

Hong WANG et al.

Acta pharmacologica Sinica, 31(12), 1541-1546 (2010-11-26)

to investigate the changing resistance to nondepolarizing muscle relaxants (NDMRs) during the first month after denervation. the denervated and innervated skeletal muscle cells were examined on days 1, 4, 7, 14, 21, and 28 after denervation. Individual denervated and innervated

Magnesium sulfate enhances non-depolarizing muscle relaxant vecuronium action at adult muscle-type nicotinic acetylcholine receptor in vitro.

Hong Wang et al.

Acta pharmacologica Sinica, 32(12), 1454-1459 (2011-10-12)

To investigate the effect of magnesium sulfate and its interaction with the non-depolarizing muscle relaxant vecuronium at adult muscle-type acetylcholine receptors in vitro. Adult muscle-type acetylcholine receptors were expressed in HEK293 cells. Drug-containing solution was applied via a gravity-driven perfusion

Quantitative analysis of the aminosteroidal non-depolarizing neuromuscular blocking agent vecuronium by LC-ESI-MS: A Postmortem Investigation.

Shawn P Vorce et al.

Journal of analytical toxicology, 32(6), 422-427 (2008-07-26)

The apparent recreational use of an aminosteroidal non-depolarizing neuromuscular blocking agent, vecuronium, is reported in this postmortem investigation. A quantitative method for the analysis of vecuronium and its active metabolite, 3-desacetylvecuronium, in blood and tissue samples was developed using liquid

View All Related Papers