D3439
D-erythro-Dihydrosphingosine 1-phosphate
≥98% (TLC), waxy solid
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About This Item
Empirical Formula (Hill Notation):
C18H40NO5P
CAS Number:
Molecular Weight:
381.49
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352211
MDL number:
Quality Level
assay
≥98% (TLC)
form
waxy solid
color
yellow
solubility
methanol: THF: water (6:3:1): >0.5 mg/mL
storage temp.
−20°C
SMILES string
CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)COP(O)(O)=O
InChI
1S/C18H40NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h17-18,20H,2-16,19H2,1H3,(H2,21,22,23)/t17-,18+/m0/s1
InChI key
YHEDRJPUIRMZMP-ZWKOTPCHSA-N
Gene Information
human ... S1PR1(1901), S1PR2(9294), S1PR3(1903), S1PR4(8698), S1PR5(53637)
Biochem/physiol Actions
Negative control for sphingosine-1-phosphate.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Related Content
Datasheet
Van Brocklyn, J.R., et al.
The Journal of Biological Chemistry, 142, 229-229 (1998)
Masayuki Sugimoto et al.
Biochemical and biophysical research communications, 533(4), 1269-1275 (2020-10-17)
Sphingomyelin synthase 2 (SMS2) regulates sphingomyelin synthesis and contributes to obesity and hepatic steatosis. Here, we investigated the effect of SMS2 deficiency on liver fibrosis in mice fed with choline-deficient, L-amino acid-defined, high-fat diet (CDAHFD) or injected with carbon tetrachloride
Sang Won Park et al.
Laboratory investigation; a journal of technical methods and pathology, 90(8), 1209-1224 (2010-05-12)
Liver failure due to ischemia and reperfusion (IR) and subsequent acute kidney injury are significant clinical problems. We showed previously that liver IR selectively reduced plasma sphinganine-1-phosphate levels without affecting sphingosine-1-phosphate (S1P) levels. Furthermore, exogenous sphinganine-1-phosphate protected against both liver