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About This Item
NACRES:
NA.51
UNSPSC Code:
41105324
description
Powered by Eupheria Biotech
Quality Level
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
CCCCAAGAGACAAGTTTCCACAGAGCCCTCATCTACCTCCTCCTCCTCCTCTGACCCCATCTTGGACCTCAACATCTCCTTGGCTGTGGCTAAAGAGAGGGCCCACCAGAAGCGCAGTAGCAAGAGGGCCCCGCAGATGGACTGGAGCAAGAAAAATGAACTCTTCAGCAACCTCTGAGCATCCCACCTCCGTGGGCTTGTGCTAGAGGGTGGGGCTGCCCACCCTACCTAGCTCCCCTTCCCTTCTCCCCAGGTGCCCACCAATCAACATTCAGATCAGCATCAGCACCCACCCCACTTCCTGACAAATCTGATTTTTCTAGAATCCTGTTCTTCCCTCACCTTAGGGAAGGAGAATGTTTGTCCTGTCTCCCTACACTTCCCTGAGGGCTTCTTCCTACCAAAGTGTCCCCTCA
Ensembl | mouse accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Gene Information
mouse ... SLC9A3R1(26941), Slc9a3r1(26941)
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
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Pseudomonas aeruginosa reduces the expression of CFTR via post-translational modification of NHERF1.
Rosa Rubino et al.
Pflugers Archiv : European journal of physiology, 466(12), 2269-2278 (2014-03-07)
Pseudomonas aeruginosa infections of the airway cells decrease apical expression of both wild-type (wt) and F508del CFTR through the inhibition of apical endocytic recycling. CFTR endocytic recycling is known to be regulated by its interaction with PDZ domain containing proteins.