RAB0960
Phosphotyrosine FER / Tyrosine-protein Kinase Fer ELISA Kit
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About This Item
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... FER(2241)
Input:
sample type: human cell lysate
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type: human cell lysate
assay range
inter-assay cv: <10%
intra-assay cv: <12%
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... FER(2241)
General description
The antibody pair provided in this kit recognizes Human Tyrosine-Phosphorylated-FER.
FER (fps/fes related) tyrosine kinase is encoded by the gene mapped to human chromosome 5q21.3. Tyrosine kinase is a cytoplasmic protein characterized with a single SH2 domain and an extensive amino terminus. The encoded protein is ubiquitously expressed.
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
FER tyrosine kinase induces signal transduction at the plasma membrane. It is implicated in the regulation of cell-cell adhesion. FER tyrosine kinase interacts with phosphatidic acid (PA) to enhance phosphorylation of cortactin, a protein that promotes actin.
Kit Components Also Available Separately
Product No.
Description
SDS & Pricing
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Storage Class
10 - Combustible liquids
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Related Content
Instructions
The Tyrosine Kinase Fer Is a Downstream Target of the PLD-PA Pathway that Regulates Cell Migration
Itoh T, et al.
Science Signaling, 2(87), ra52-ra52 (2009)
Characterization of a de novo balanced translocation in a patient with moderate mental retardation and dysmorphic features
Haddad M R, et al.
European Journal of Medical Genetics, 52(4), 211-217 (2009)
The cytoplasmic tyrosine kinase FER is associated with the catenin-like substrate pp120 and is activated by growth factors.
Kim L and Wong T W
Molecular Cell Biology, 15(8), 4553-4561 (1995)