N5757
α-Naphthoflavone
≥98%
Synonym(s):
alpha-Naphthoflavone, 7,8-Benzoflavone
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About This Item
Empirical Formula (Hill Notation):
C19H12O2
CAS Number:
Molecular Weight:
272.30
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-071-1
Beilstein/REAXYS Number:
210494
MDL number:
InChI key
VFMMPHCGEFXGIP-UHFFFAOYSA-N
InChI
1S/C19H12O2/c20-17-12-18(14-7-2-1-3-8-14)21-19-15-9-5-4-6-13(15)10-11-16(17)19/h1-12H
SMILES string
O=C1C=C(Oc2c1ccc3ccccc23)c4ccccc4
assay
≥98%
Quality Level
Gene Information
human ... ADORA3(140), CYP1A2(1544), PRKDC(5591)
rat ... Adora1(29290), Adora2a(25369)
technique(s)
titration: suitable
color
white to yellow
storage temp.
2-8°C
Related Categories
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Min Ji Kim et al.
Environmental health perspectives, 120(4), 508-514 (2012-01-21)
Epidemiological studies emphasize the possible role of persistent organic pollutants (POPs) in obesity and the metabolic syndrome. These pollutants are stored in adipose tissue (AT). Our aim was to study the effects of POPs on human adipose cells and rodent
Po-Lin Liao et al.
Experimental dermatology, 21(7), 546-548 (2012-06-22)
Ageing is a complex and multifactorial process resulting in several functional and aesthetic changes to the skin. We found that α-Naphthoflavone (α-NF) concentration-dependently induced pro-collagen type I protein expression and inhibited MMP-1 protein expression, in both normal and UVB-irradiated cells.
Iain A Murray et al.
Molecular pharmacology, 79(3), 508-519 (2010-12-04)
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With early assessment of inhibitory properties of drug candidates and their circulating metabolites toward cytochrome P450 enzymes, drug attrition, especially later in the drug development process, can be decreased. Here we describe the development and validation of an at-line nanofractionation
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Corynoline (CRL), an isoquinoline alkaloid, is the major constituent derived from Corydalis bungeana Herba, which is a well-known Chinese herbal medicine widely used in many prescriptions. The purpose of this study was to comprehensively investigate the metabolism and bioactivation of
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