30-4310
Trifluoroacetic acid
SAJ special grade, ≥99.0%
Synonym(s):
TFA
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About This Item
Linear Formula:
CF3COOH
CAS Number:
Molecular Weight:
114.02
EC Number:
200-929-3
UNSPSC Code:
12352106
PubChem Substance ID:
Beilstein/REAXYS Number:
742035
MDL number:
Assay:
≥99.0%
Form:
liquid
Grade:
SAJ special grade
Product Name
Trifluoroacetic acid, SAJ special grade, ≥99.0%
InChI
1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)
InChI key
DTQVDTLACAAQTR-UHFFFAOYSA-N
SMILES string
OC(C(F)(F)F)=O
grade
SAJ special grade
vapor density
3.9 (vs air)
vapor pressure
97.5 mmHg ( 20 °C)
assay
≥99.0%
form
liquid
availability
available only in Japan
refractive index
n20/D 1.3 (lit.)
pH
1 (20 °C, 1 g/L)
bp
72.4 °C (lit.)
mp
−15.4 °C (lit.)
solubility
H2O: soluble
density
1.489 g/mL at 20 °C (lit.)
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Related Categories
Application
- New fabric phase sorptive extraction for nondestructive analysis of heritage textile samples.: This study introduces a novel extraction method utilizing trifluoroacetic acid for analyzing heritage textiles without causing damage. The technique improves the efficiency and accuracy of detecting and quantifying analytes in historical fabrics (Tanasescu et al., 2024).
- Alpibectir: Early Qualitative and Quantitative Metabolic Profiling from a First Time in Human Study by Combining (19)F-NMR, (1)H-NMR and HRMS Analyses.: This research employs trifluoroacetic acid in metabolic profiling to enhance the resolution and accuracy of NMR and HRMS analyses, providing critical insights into the early stages of drug metabolism (Weston et al., 2024).
- Preparation and characterization of stationary phase gradients on C8 liquid chromatography columns.: The use of trifluoroacetic acid in preparing stationary phase gradients significantly improves the performance and stability of C8 columns in liquid chromatography, optimizing the separation of complex mixtures (Cecil et al., 2024).
- Optimization of Cyanocobalamin (Vitamin B(12)) Sorption onto Mesoporous Superparamagnetic Iron Oxide Nanoparticles.: This article details the use of trifluoroacetic acid in the optimization process of sorbing vitamin B12 onto nanoparticles, enhancing the efficacy of nutrient delivery systems (Flieger et al., 2024).
- Development, Validation, and Application of High-Performance Liquid Chromatography with Diode-Array Detection Method for Simultaneous Determination of Ginkgolic Acids and Ginkgols in Ginkgo biloba.: Trifluoroacetic acid is utilized in this method development for HPLC, enabling accurate and simultaneous determination of multiple compounds in Ginkgo biloba extracts (Boateng et al., 2024).
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 2
flash_point_f
>212.0 °F - Pensky-Martens closed cup
flash_point_c
> 100 °C - Pensky-Martens closed cup
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Guillaume Plourde et al.
Lancet (London, England), 386(10009), 2192-2203 (2015-09-29)
Transradial access for cardiac catheterisation results in lower bleeding and vascular complications than the traditional transfemoral access route. However, the increased radiation exposure potentially associated with transradial access is a possible drawback of this method. Whether transradial access is associated
Yukiko Enomoto-Rogers et al.
Carbohydrate polymers, 92(2), 1827-1834 (2013-02-13)
Fully substituted glucomannan triacetate (GMTAc) (degree of substitution (DS)=3.0) was prepared from konjac glucomannan (KGM) treated with acetic acid and trifluoroacetic anhydride (TFAA). The peaks in the (1)H- and (13)C NMR spectra of GMTAc were assigned in detail based on
Wen Zhang et al.
Methods (San Diego, Calif.), 81, 50-55 (2015-02-28)
Clinical tissue samples provide valuable information for understanding human diseases. One major type of clinical tissue sample that is amenable to various kinds of analysis is fresh frozen and optimal cutting temperature (OCT)-embedded primary patient tissue. Recent advances in mass
Oskar Karlsson et al.
Archives of toxicology, 89(3), 423-436 (2014-05-07)
The environmental neurotoxin β-N-methylamino-L-alanine (BMAA) has been implicated in the etiology of neurodegenerative disease, and recent studies indicate that BMAA can be misincorporated into proteins. BMAA is a developmental neurotoxicant that can induce long-term learning and memory deficits, as well
Kathrin Bellmann-Sickert et al.
The Journal of biological chemistry, 290(3), 1752-1759 (2014-11-27)
Bacterial cell membranes contain several protein pumps that resist the toxic effects of drugs by efficiently extruding them. One family of these pumps, the small multidrug resistance proteins (SMRs), consists of proteins of about 110 residues that need to oligomerize
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