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Merck

P1722

Potassium citrate tribasic monohydrate

crystals, meets USP testing specifications

Synonym(s):

Citric acid tripotassium salt, Tripotassium citrate

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About This Item

Linear Formula:
HOC(COOK)(CH2COOK)2 · H2O
CAS Number:
Molecular Weight:
324.41
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
231-905-0
MDL number:
Beilstein/REAXYS Number:
3924344
Assay:
100.10%
Form:
crystals
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Product Name

Potassium citrate tribasic monohydrate, meets USP testing specifications

InChI key

PJAHUDTUZRZBKM-UHFFFAOYSA-K

InChI

1S/C6H8O7.3K.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;1H2/q;3*+1;/p-3

SMILES string

O.[K+].[K+].[K+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O

agency

USP/NF, meets USP testing specifications

Quality Level

assay

100.10%

form

crystals

mp

275 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

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General description

Potassium citrate tribasic monohydrate (KCTM) is a potassium salt that has been reported to be efficient in forming aqueous two-phase system (ATPS) with UCON 50-HB-5100, a random copolymer. This product is a high quality pharmacopoeia product that meets the testing specifications of USP (United States Pharmacopoeia). It can be employed in research and pilot studies.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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(Liquid+ liquid) equilibria of polymer-salt aqueous two-phase systems for laccase partitioning: UCON 50-HB-5100 with potassium citrate and (sodium or potassium) formate at 23?C.
Lladosa E, et al.
The Journal of Chemical Thermodynamics, 55, 166-171 (2012)
Maria Goretti Moreira Guimarães Penido et al.
Pediatric nephrology (Berlin, Germany), 27(1), 123-130 (2011-07-23)
Children with idiopathic hypercalciuria (IH) may have a reduced bone mineral density (BMD), which could impact on bone health in adulthood. There is currently no strong evidence for a preferred treatment of such children. The aim of our study was
Astrid Starke et al.
Clinical journal of the American Society of Nephrology : CJASN, 7(9), 1461-1472 (2012-07-10)
Acidosis and transplantation are associated with increased risk of bone disturbances. This study aimed to assess bone morphology and metabolism in acidotic patients with a renal graft, and to ameliorate bone characteristics by restoration of acid/base homeostasis with potassium citrate.
Pierre Cochat et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 27(5), 1729-1736 (2012-05-02)
Primary hyperoxaluria Type 1 is a rare autosomal recessive inborn error of glyoxylate metabolism, caused by a deficiency of the liver-specific enzyme alanine:glyoxylate aminotransferase. The disorder results in overproduction and excessive urinary excretion of oxalate, causing recurrent urolithiasis and nephrocalcinosis.
Arun Gopalakrishnan et al.
Clinical and experimental nephrology, 15(5), 745-748 (2011-06-01)
Fanconi-Bickel syndrome is a rare autosomal recessive disorder characterized by hepatorenal glycogen accumulation, proximal renal tubular dysfunction and impaired utilization of glucose and galactose. Most cases have been reported from Europe, Japan, Turkey and the Mediterranean belt. We report a

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