P2256

Sodium pyruvate

Name: Sodium pyruvate
Brand: SIAL

≥99%, powder, ReagentPlus^®

Synonym(s):

α-Ketopropionic acid sodium salt, 2-Oxopropanoic acid sodium salt, Pyruvic acid sodium salt

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About This Item

Linear Formula:

CH₃COCOONa

CAS Number:

113-24-6

Molecular Weight:

110.04

NACRES:

NA.21

PubChem Substance ID:

24898303

UNSPSC Code:

12352100

EC Number:

204-024-4

MDL number:

MFCD00002586

Beilstein/REAXYS Number:

3568341

assay:

≥99%

form:

powder

solubility:

H₂O: 100 mg/mL, clear, colorless to faintly yellow

Product Name

Sodium pyruvate, ReagentPlus^®, ≥99%

InChI key

DAEPDZWVDSPTHF-UHFFFAOYSA-M

InChI

1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1

SMILES string

[Na+].CC(=O)C([O-])=O

product line

ReagentPlus^®

assay

≥99%

form

powder

loss

≤0.5% loss on drying

mp

>300 °C (lit.)

solubility

H₂O: 100 mg/mL, clear, colorless to faintly yellow

cation traces

heavy metals (as Pb): ≤20 ppm

functional group

ketone

storage temp.

2-8°C

Quality Level

200

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Related Categories

Chemistry & Biochemicals

Lab Chemicals

Salts

Application

Sodium pyruvate has been used:

To prepare Bull Tyrode′s albumin-lactate-pyruvate diluent.
In pyruvate tolerance test.
To prepare oligodendrocyte culture medium.

General description

Sodium pyruvate (SP) is a simplest keto-acid. It crystallizes as very thin plates and belongs to the monoclinic system. Its utility in Knoevenagel condensation carried out in an aqueous medium has been examined. The standard molar enthalpy of formation and molar enthalpy of dissolution of SP at infinite dilution have been obtained. Its efficacy in treating mitochondrial DNA depletion syndromes has been investigated.

Other Notes

Go to Redi-Dri^™ Product Listing 792500

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

pictograms

GHS07

signalword

Warning

hcodes

H317,H319

pcodes

P261 - P264 - P272 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1B

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Pyruvate therapy for mitochondrial DNA depletion syndrome.

Saito K, et al.

Biochim. Biophys. Acta Gen. Subj., 1820(5), 632-636 (2012)

"On Water": Rapid Knoevenagel Condensation Using Sodium Pyruvate.

Heravi MM, et al.

Letters in Organic Chemistry, 3(4), 297-299 (2006)

The crystal structure of sodium pyruvate.

Tavale SS, et al.

Acta Crystallographica, 14(12), 1281-1286 (1961)

Crystal structure and thermochemical properties of a novel coordination compound sodium pyruvate C₃H₃O₃Na(s).

Gao ZF, et al.

The Journal of Chemical Thermodynamics, 78, 189-196 (2014)

Regulation of glucose tolerance and sympathetic activity by MC4R signaling in the lateral hypothalamus.

Donald A Morgan et al.

Diabetes, 64(6), 1976-1987 (2015-01-22)

Melanocortin 4 receptor (MC4R) signaling mediates diverse physiological functions, including energy balance, glucose homeostasis, and autonomic activity. Although the lateral hypothalamic area (LHA) is known to express MC4Rs and to receive input from leptin-responsive arcuate proopiomelanocortin neurons, the physiological functions

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