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Merck

Y0001194

Resveratrol

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

3,4′,5-Trihydroxy-trans-stilbene, 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol

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About This Item

Empirical Formula (Hill Notation):
C14H12O3
CAS Number:
501-36-0
Molecular Weight:
228.24
NACRES:
NA.24
PubChem Substance ID:
329831299
UNSPSC Code:
41116107
MDL number:
MFCD00133799

Product Name

Resveratrol, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+

SMILES string

Oc1ccc(cc1)\C=C\c2cc(O)cc(O)c2

InChI key

LUKBXSAWLPMMSZ-OWOJBTEDSA-N

grade

pharmaceutical primary standard

API family

resveratrol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

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Related Categories

Application

Selective inhibitor of COX−1.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

>392.0 °F - closed cup - (External MSDS)

flash_point_c

> 200.0 °C - closed cup - (External MSDS)

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Alexandra Maier-Salamon et al.
Annals of the New York Academy of Sciences, 1290, 98-106 (2013-07-17)
Resveratrol exhibits a variety of biological and pharmacological activities despite its extensive metabolism to sulfates and glucuronides in the intestine and liver. The metabolism of resveratrol is cell specific and strongly correlates with enzyme expression levels. However, a high rate
Mary Ann Augustin et al.
Annals of the New York Academy of Sciences, 1290, 107-112 (2013-07-17)
There has been interest in the use of trans-resveratrol as a natural preventative agent for improving health and alleviating a range of diseases. However, resveratrol has low bioavailability, and this has been associated with its poor water solubility, its low
Silvie Timmers et al.
Annals of the New York Academy of Sciences, 1290, 83-89 (2013-07-17)
The number of people suffering from metabolic disorders is dramatically increasing worldwide. The need for new therapeutic strategies to combat this growing epidemic of metabolic diseases is therefore also increasing. In 2003, resveratrol was discovered to be a small molecule
Morten Møller Poulsen et al.
Annals of the New York Academy of Sciences, 1290, 74-82 (2013-07-17)
In the search for novel preventive and therapeutic modalities in the management of metabolic diseases and obesity, resveratrol has attracted great attention over the past decades. Preclinical trials suggest that resveratrol mimics the metabolic effects of calorie restriction (CR) via
Agneta Oskarsson et al.
The Prostate, 74(8), 839-851 (2014-03-13)
Resveratrol (RSV) and resveratrol analogs have a potential use in prostate cancer chemoprevention due to effects on for example, cell growth, apoptosis, angiogenesis, and metastasis. However, inhibition of CYP17A1, a key enzyme in the androgen biosynthesis and a target for
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