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D13208

1,4-Diaminobutane

Name: 1,4-Diaminobutane
Brand: ALDRICH

99%

Synonym(s):

1,4-Butanediamine, Putrescine, Tetramethylenediamine

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About This Item

Linear Formula:

NH₂(CH₂)₄NH₂

CAS Number:

110-60-1

Molecular Weight:

88.15

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24893255

EC Number:

203-782-3

Beilstein/REAXYS Number:

605282

MDL number:

MFCD00008235

Assay:

99%

Form:

solid

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Properties

Quality Level

200

assay

99%

form

solid

expl. lim.

9.08 %

refractive index

n20/D 1.457 (lit.)

bp

158-160 °C (lit.)

mp

25-28 °C (lit.)

density

0.877 g/mL at 25 °C (lit.)

SMILES string

NCCCCN

InChI

1S/C4H12N2/c5-3-1-2-4-6/h1-6H2

InChI key

KIDHWZJUCRJVML-UHFFFAOYSA-N

Gene Information

rat ... Odc1(24609)

Description

Application

GABA precursor in many biological systems and synthon for amido-ureas.

pictograms

GHS06,GHS05

signalword

Danger

hcodes

H290,H302,H311,H314,H330

pcodes

P260 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 1

flash_point_f

113.0 °F - closed cup

flash_point_c

45 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Excitatory amino acid receptors mediate the glutamate-induced release of GABA synthesized from putrescine in cultured cells of embryonic avian retina.

M C de Mello et al.

Neurochemistry international, 22(3), 249-253 (1993-03-01)

Cultured retina cells from chick embryos took up [3H]putrescine and approx 10.8% of the incorporated amine was converted into [3H]GABA. The putrescine-derived GABA accumulated in a pool that was released in the medium at a rate corresponding to 3.66% of

Journal of the Chemical Society. Perkin Transactions 1, 3179-3179 (1992)

Genome-wide PhoB binding and gene expression profiles reveal the hierarchical gene regulatory network of phosphate starvation in Escherichia coli.

Chi Yang et al.

PloS one, 7(10), e47314-e47314 (2012-10-17)

The phosphate starvation response in bacteria has been studied extensively for the past few decades and the phosphate-limiting signal is known to be mediated via the PhoBR two-component system. However, the global DNA binding profile of the response regulator PhoB

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