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About This Item
Empirical Formula (Hill Notation):
C35H69NO4
CAS Number:
Molecular Weight:
567.93
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
17:0(2R-OH) Ceramide, Avanti Research™ - A Croda Brand 860817P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (860817P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860817P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCCCCCCC)=O)CO
InChI
1S/C35H69NO4/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33(38)32(31-37)36-35(40)34(39)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h27,29,32-34,37-39H,3-26,28,30-31H2,1-2H3,(H,36,40)/b29-27+/t32-,33+,34+/m0/s1
InChI key
MBKBHFOACJJHAN-NBVWUYLUSA-N
General description
17:0(2R-OH) Ceramide is a 2R hydroxylated heptadecanoic acid-containing sphingolipid. It is present mainly in epidermis.
Biochem/physiol Actions
Hydroxy fatty acids (hFA)-sphingolipids play a vital role in cell signaling. They also help in cell differentiation and apoptosis. hFA-ceramides are involved in the formation of the epidermal barrier. Fatty acid 2-hydroxylases (FA2H) synthesize hFA-ceramides. Mutations of FA2H have been linked to neurological disorders like spastic paraparesis in humans and leukodystrophy. hFA-ceramides in the cell membrane play a crucial role in imparting the PM02734 drug with anti-tumor activity.
Packaging
5 mL Amber Glass Screw Cap Vial (860817P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
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