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About This Item
Empirical Formula (Hill Notation):
C35H69NO4
CAS Number:
Molecular Weight:
567.93
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
17:0(2S-OH) Ceramide, Avanti Research™ - A Croda Brand 860818P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (860818P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860818P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@@H](O)CCCCCCCCCCCCCCC)=O)CO
InChI key
MBKBHFOACJJHAN-GTQKJTMESA-N
General description
Ceramides with 2-hydroxy fatty acids (hFA) group are mainly found in the epidermis. 17:0(2S-OH) Ceramide is a unique ceramide containing 17C long chain base fatty acid (heptadecanoic acid)-with 2′-hydroxyl group in S configuration.
Biochem/physiol Actions
Hydroxy fatty acids (hFA)-sphingolipids helps in cell signaling. They also facilitate cell differentiation and apoptosis. hFA-ceramides in epidermis helps in permeability barrier function. hFA-ceramides are synthesized by fatty acid 2-hydroxylase (FA2H). Mutations of FA2H leads to the development of neurological disorders such as leukodystrophy and spastic paraparesis in humans. hFA-ceramides in the cell membrane are essential for PM02734 drug to exhibit its anti-tumor activity.
Packaging
5 mL Amber Glass Screw Cap Vial (860818P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
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