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Merck

D7909

Dicyclomine hydrochloride

≥99% (TLC), powder

Synonym(s):

2-(Diethylamino)ethyl 1-cyclohexylcyclohexane-1-carboxylate hydrochloride, [1,1-Bicyclohexyl]-1-carboxylic acid 2-(diethylamino)ethyl ester hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C19H35NO2 · HCl
CAS Number:
Molecular Weight:
345.95
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-671-1
MDL number:
Assay:
≥99% (TLC)
Form:
powder
Quality level:
Technical Service
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Quality Level

assay

≥99% (TLC)

form

powder

color

off-white

solubility

H2O: 50 mg/mL

SMILES string

CCN(CCOC(C1(C2CCCCC2)CCCCC1)=O)CC.[Cl]

InChI

1S/C19H35NO2.ClH/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17;/h17H,3-16H2,1-2H3;1H

InChI key

GUBNMFJOJGDCEL-UHFFFAOYSA-N

Biochem/physiol Actions

Competitive muscarinic acetylcholine receptor antagonist.


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Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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American Gastroenterological Association institute medical position statement on the use of gastrointestinal medication in pregnancy.
Arthur Staroselsky et al.
Gastroenterology, 132(2), 824-825 (2007-01-31)
Andrea M Robinson et al.
Journal of psychopharmacology (Oxford, England), 26(8), 1143-1150 (2011-09-06)
The cholinergic system is known to be necessary for normal attentional processing. However, the receptors and mechanisms mediating the effects of acetylcholine on attention remain unclear. Previous work in our laboratory suggested that cholinergic muscarinic receptors are critical for maintaining
Surabi Veeraragavan et al.
Psychopharmacology, 217(1), 143-151 (2011-04-14)
Muscarinic acetylcholine receptors (mAChR) are G protein-coupled receptors, widely expressed in the CNS. Electrophysiological and molecular studies have provided evidence for overactive M1 receptor signaling in the fragile X knockout (Fmr1 KO) mouse model, suggesting the involvement of the M1