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Merck

SAB5600022

Anti-Histone H3 (unmodified Lys4) antibody, Rabbit monoclonal

recombinant, expressed in HEK 293 cells, clone RM186, purified immunoglobulin

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Product Name

Anti-Histone H3 (unmodified Lys4) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM186, purified immunoglobulin

recombinant

expressed in HEK 293 cells

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

RM186, monoclonal
recombinant monoclonal

form

buffered aqueous glycerol solution

species reactivity

human

concentration

~1 mg/mL

technique(s)

ELISA: 0.5- 1  μg/mL
immunocytochemistry: 0.5-2 μg/mL
western blot: 1-2 μg/mL

isotype

IgG

NCBI accession no.

8350

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... H3C1(8350)

Biochem/physiol Actions

This antibody recognizes Histone H3 that is unmodified at Lys4 and does not recognize acetylated or methylated Lys4. The antibody binding specificity allows for modifications of Arg2, Thr3, and/or other modifications in Histone H3.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Immunogen

Synthetic peptide corresponding to the N-terminus of Histone H3.

Physical form

Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
Q0300944
P1100782

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Antonella Muscella et al.
Journal of neurochemistry, 153(4), 525-538 (2019-11-16)
Following peripheral nerve injury, remnant Schwann cells adopt a migratory phenotype and remodel the extracellular matrix allowing axonal regrowth. Although much evidence has demonstrated that TGF-β1 promotes glioma cell motility and induces the expression of extracellular matrix proteins, the effects

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