SAB5701750
Anti-Phospho-CFL1-S3 antibody produced in rabbit
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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
mouse, human, rat
Application:
IHC, WB
Citations:
-
biological source
rabbit
Quality Level
antibody product type
primary antibodies
clone
polyclonal
form
liquid
species reactivity
mouse, human, rat
concentration
0.71 mg/mL
technique(s)
immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer3)
Gene Information
human ... CFL1(1072)
General description
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
Immunogen
A phospho specific peptide corresponding to residues surrounding S3 of human CFL1
Physical form
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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