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SML3251

GRL-1720

≥98% (HPLC)

Synonym(s):

1H-Indole-4-carboxylic acid 5-chloro-3-pyridinyl ester, 5-Chloro-3-pyridinyl 1H-indole-4-carboxylate, GRL 0496, GRL-0496, GRL0496

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About This Item

Empirical Formula (Hill Notation):
C14H9ClN2O2
CAS Number:
1087243-14-8
Molecular Weight:
272.69
UNSPSC Code:
51111800
NACRES:
NA.77
MDL number:
MFCD34471049
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: ≥2 mg/mL, clear

storage temp.

2-8°C

SMILES string

ClC1=CN=CC(OC(C2=CC=CC3=C2C=CN3)=O)=C1

InChI key

BOSZJNSICHFHMA-UHFFFAOYSA-N

Biochem/physiol Actions

GRL-1720 is an irreversible, covalent inhibitor of SARS-CoV-2 Mpro that blocks virus replication. GRL-1720 protects VeroE6 cells form SARS-CoV-2WK-521 infection. It shows no significant cytotoxicity to several cell lines.
Irreversible, covalent inhibitor of SARS-CoV-2 Mpro that blocks virus replication

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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