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Merck

115169

Tetramethylthiourea

98%

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About This Item

Linear Formula:
(CH3)2NCSN(CH3)2
CAS Number:
Molecular Weight:
132.23
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
220-488-0
Beilstein/REAXYS Number:
1744916
MDL number:
Assay:
98%
Form:
solid
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InChI key

MNOILHPDHOHILI-UHFFFAOYSA-N

InChI

1S/C5H12N2S/c1-6(2)5(8)7(3)4/h1-4H3

SMILES string

CN(C)C(=S)N(C)C

assay

98%

form

solid

bp

245 °C (lit.)

mp

75-77 °C (lit.)

storage temp.

2-8°C

Quality Level

General description

Tetramethylthiourea molecule shows crystallographic two-fold symmetry with weak hydrogen bond packing, which connects the molecules to form layers.

Application

Tetramethylthiourea forms BF3 adduct with tetramethylselenourea.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


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J Palassis
American Industrial Hygiene Association journal, 41(2), 91-97 (1980-02-01)
Tetramethyl and ethylene thiourea are collected from air using midget impingers containing 15 mL water. Ethylene thiourea may also be collected from air using PVC or cellulose ester membrane filters which are then extracted with water. Pentacyanoamineferrate reagent is added
Urea-boron trihalide adducts. IV. Ionic-covalent equilibria in the tetramethylthiourea-BF3 and tetramethylselenourea-BF3 systems and the influence of B2F7-formation.
Hartman JS, et al.
Canadian Journal of Chemistry, 54(7), 1121-1129 (1976)
J Bouvet et al.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 5(4), 345-355 (1987-01-01)
A morphometric analysis of Purkinje cells in the developing cerebellar cortex of the chick was performed in normal animals and embryos made hypothyroid by one or two spaced injections of tetramethylthiourea. Profiles of 162 Purkinje cells, from Golgi-Cox treated sections
Andrew Churg et al.
Toxicology and applied pharmacology, 208(1), 37-45 (2005-09-17)
Air pollution particles (PM) are known to elicit an acute inflammatory response in vivo that is mediated in part through PM-induced activation of the NF-kappaB signaling pathway. Many of the details of this process and particularly where in the cell
T Sakamoto et al.
The American journal of physiology, 276(6 Pt 1), C1391-C1397 (1999-06-11)
Obesity is associated with hyperinsulinemia and elevated concentrations of tumor necrosis factor-alpha (TNF-alpha) in adipose tissue. TNF-alpha has been implicated as an inducer of the synthesis of plasminogen activator inhibitor-1 (PAI-1), the primary physiological inhibitor of fibrinolysis, mediated by plasminogen

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