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Merck

141879

(−)-Lobeline hydrochloride

98%

Synonym(s):

α-Lobeline hydrochloride, L-Lobeline hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C22H27NO2 · HCl
CAS Number:
134-63-4
Molecular Weight:
373.92
UNSPSC Code:
12352005
NACRES:
NA.22
PubChem Substance ID:
24848513
EC Number:
205-150-2
Beilstein/REAXYS Number:
3920196
MDL number:
MFCD00082455
Assay:
98%

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Quality Level

100

InChI key

MKMYPTLXLWOUSO-NFQNBQCWSA-N

InChI

1S/C22H27NO2.ClH/c1-23-19(15-21(24)17-9-4-2-5-10-17)13-8-14-20(23)16-22(25)18-11-6-3-7-12-18;/h2-7,9-12,19-21,24H,8,13-16H2,1H3;1H/t19-,20+,21-;/m0./s1

SMILES string

Cl[H].CN1[C@@H](CCC[C@@H]1CC(=O)c2ccccc2)C[C@H](O)c3ccccc3

assay

98%

optical activity

[α]20/D −56.8°, c = 2 in H2O

mp

183-185 °C (dec.) (lit.)

functional group

hydroxyl, ketone, phenyl

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pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
STBK7398
STBK6659
STBK0697
STBF5046V
STBD0688V

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Jeong-Ho Park et al.
FEBS letters, 590(4), 493-500 (2016-01-24)
The intestine is involved in digestion and absorption, as well as the regulation of metabolism upon sensation of the internal intestinal environment. Enteroendocrine cells are thought to mediate these internal intestinal chemosensory functions. Using the CaLexA (calcium-dependent nuclear import of
Hany Km Dweck et al.
eLife, 10 (2021-02-23)
Although most Drosophila species lay eggs in overripe fruit, the agricultural pest Drosophila suzukii lays eggs in ripe fruit. We found that changes in bitter taste perception have accompanied this adaptation. We show that bitter-sensing mutants of Drosophila melanogaster undergo
Jaekyun Choi et al.
eNeuro, 7(2) (2020-03-30)
Feeding, a critical behavior for survival, consists of a complex series of behavioral steps. In Drosophila larvae, the initial steps of feeding are food choice, during which the quality of a potential food source is judged, and ingestion, during which
Michelle Bui et al.
BMC neuroscience, 20(1), 27-27 (2019-06-19)
The mosquito Aedes aegypti has a wide variety of sensory pathways that have supported its success as a species as well as a highly competent vector of numerous debilitating infectious pathogens. Investigations into mosquito sensory systems and their effects on
Hany K M Dweck et al.
Current biology : CB, 30(1), 17-30 (2019-12-17)
Taste systems detect a vast diversity of toxins, which are perceived as bitter. When a species adapts to a new environment, its taste system must adapt to detect new death threats. We deleted each of six commonly expressed bitter gustatory receptors (Grs)
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