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Merck

150215

9(10H)-Acridanone

99%

Synonym(s):

Acridone, 9,10-Dihydro-9-oxoacridine

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About This Item

Empirical Formula (Hill Notation):
C13H9NO
CAS Number:
Molecular Weight:
195.22
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
209-434-7
Beilstein/REAXYS Number:
7104
MDL number:
Assay:
99%
Form:
solid
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InChI key

FZEYVTFCMJSGMP-UHFFFAOYSA-N

InChI

1S/C13H9NO/c15-13-9-5-1-3-7-11(9)14-12-8-4-2-6-10(12)13/h1-8H,(H,14,15)

SMILES string

O=C1c2ccccc2Nc3ccccc13

assay

99%

form

solid

mp

>300 °C (lit.)

λmax

380 nm, 399 nm (2nd)

Quality Level

Gene Information

human ... ABCB1(5243)

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Application

9(10H)-Acridanone (acridone) was used in the preparation of methyl 9,10-dihydro-9-oxoacridine-10-pentanoate.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Dadi Chen et al.
Biotechnology for biofuels, 13, 130-130 (2020-07-24)
Considerable interest has been expressed in the development of anaerobic digestion (AD) of straw to solve the environmental problems caused by the dumping and burning of straw and to generate clean energy. However, the poor biodegradability of straw and the
Giuseppe Manfroni et al.
Journal of medicinal chemistry, 52(10), 3354-3365 (2009-04-25)
We report the synthesis and structure-activity relationship (SAR) of a large series of acridones and acridone-fragment derivatives designed on the basis of the selective antihepatitis C virus (HCV) activity shown by acridone 2, previously studied as a potential antibovine viral
Jatinder Kaur et al.
Chemical communications (Cambridge, England), 47(15), 4472-4474 (2011-03-08)
Acridones carrying an appropriate substituent at N-10 showed significant fluorescence changes on interacting with ATP in HEPES buffer at pH 7.2. The selectivity and sufficient binding of these probes with ATP could be useful for monitoring of metabolic processes.
Anton V Dubrovskiy et al.
The Journal of organic chemistry, 77(24), 11232-11256 (2012-12-05)
A novel, efficient route to biologically and pharmaceutically important o-(dimethylamino)aryl ketones, acridones, acridinium salts, and 1H-indazoles has been developed starting from readily available hydrazones of aldehydes and o-(trimethylsilyl)aryl triflates. The reaction proceeds through arynes under mild conditions, tolerates a wide
Jacob M Goldberg et al.
Journal of the American Chemical Society, 134(14), 6088-6091 (2012-04-05)
Fluorescent probe pairs that can be selectively excited in the presence of Trp and Tyr are of great utility in studying conformational changes in proteins. However, the size of these probe pairs can restrict their incorporation to small portions of

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