211281
9-Phenanthrol
technical grade
Synonym(s):
9-Hydroxyphenanthrene
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About This Item
Empirical Formula (Hill Notation):
C14H10O
CAS Number:
Molecular Weight:
194.23
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
207-602-4
MDL number:
grade
technical grade
Quality Level
mp
139-143 °C (lit.)
SMILES string
Oc1cc2ccccc2c3ccccc13
InChI
1S/C14H10O/c15-14-9-10-5-1-2-6-11(10)12-7-3-4-8-13(12)14/h1-9,15H
InChI key
DZKIUEHLEXLYKM-UHFFFAOYSA-N
Application
9-Phenanthrol was used to investigate C K-edge and O K-edge near-edge X-ray absorption fine structure (NEXAFS) spectra of single-wall carbon nanotubes.
Biochem/physiol Actions
9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Eric C Lin et al.
Frontiers in cellular neuroscience, 11, 182-182 (2017-07-18)
Temporal lobe epilepsy is characterized by recurrent seizures in one or both temporal lobes of the brain; some
T Grand et al.
British journal of pharmacology, 153(8), 1697-1705 (2008-02-26)
TRPM4 and TRPM5 are calcium-activated non-selective cation channels with almost identical characteristics. TRPM4 is detected in several tissues including heart, kidney, brainstem, cerebral artery and immune system whereas TRPM5 expression is more restricted. Determination of their roles in physiological processes
Ana Mrejeru et al.
The Journal of physiology, 589(Pt 10), 2497-2514 (2011-04-14)
Nigral dopamine neurons are transiently activated by high frequency glutamatergic inputs relaying reward-predicting sensory information. The tonic firing pattern of dopamine cells responds to these inputs with a transient burst of spikes that requires NMDA receptors. Here, we show that