38827
4,4′-Dimethoxytriphenylmethyl chloride
≥97.0% (HPLC)
Synonym(s):
4,4′-Dimethoxytrityl chloride, Chloro-4,4′-dimethoxytriphenylmethane, DMT, DMT-Cl
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About This Item
Empirical Formula (Hill Notation):
C21H19ClO2
CAS Number:
Molecular Weight:
338.83
UNSPSC Code:
12352101
NACRES:
NA.22
PubChem Substance ID:
EC Number:
255-002-6
Beilstein/REAXYS Number:
2471942
MDL number:
Assay:
≥97.0% (HPLC)
Quality Segment
assay
≥97.0% (HPLC)
mp
123-125 °C
functional group
chloro, phenyl
SMILES string
COc1ccc(cc1)C(Cl)(c2ccccc2)c3ccc(OC)cc3
InChI
1S/C21H19ClO2/c1-23-19-12-8-17(9-13-19)21(22,16-6-4-3-5-7-16)18-10-14-20(24-2)15-11-18/h3-15H,1-2H3
InChI key
JBWYRBLDOOOJEU-UHFFFAOYSA-N
Gene Information
human ... HTR2A(3356), HTR2B(3357), HTR2C(3358)
rat ... Htr1a(24473), Htr2a(29595)
Application
4,4′-Dimethoxytriphenylmethyl chloride (DMTrCl) can be used as a protecting agent:
- For hydroxyl group of nucleosides/nucleotides as its O-(4,4′-dimethoxytrityl)derivative.
- For 10 sulfhydryl group of oligonucleotide analogs as its DMTr thioether.
Other Notes
Useful protecting-group reagent; Removal
signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
Storage Class
8B - Non-combustible corrosive hazardous materials
wgk
WGK 3
ppe
Eyeshields, Gloves, type N95 (US)
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