52200
Hexacosanoic acid
technical, ≥90% (GC)
Synonym(s):
Cerotic acid, Cerotinic acid
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About This Item
Linear Formula:
CH3(CH2)24COOH
CAS Number:
Molecular Weight:
396.69
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-040-2
Beilstein/REAXYS Number:
1799681
MDL number:
Product Name
Hexacosanoic acid, technical, ≥90% (GC)
InChI
1S/C26H52O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26(27)28/h2-25H2,1H3,(H,27,28)
InChI key
XMHIUKTWLZUKEX-UHFFFAOYSA-N
SMILES string
CCCCCCCCCCCCCCCCCCCCCCCCCC(O)=O
grade
technical
assay
≥90% (GC)
mp
84-88 °C
functional group
carboxylic acid
Quality Level
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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H W Moser et al.
Pediatric research, 16(3), 172-175 (1982-03-01)
Amniocentesis was performed in two women heterozygous for adrenoleukodystrophy (ALD). One fetus was male, and the hexacosanoic acid (C26) level in the cultured amniotic cells was 0.808 microgram per mg of protein, compared to 0.104 +/- 0.069 (S.D.) in controls.
Pedro Brites et al.
Brain : a journal of neurology, 132(Pt 2), 482-492 (2008-11-22)
Peroxisomes are organelles responsible for multiple metabolic pathways including, the biosynthesis of plasmalogens, a class of phospholipids, and the beta-oxidation of very-long-chain fatty acids (VLCFA). Lack of peroxisomes or dysfunction in any of their normal functions is the cellular basis
A two-year trial of oleic and erucic acids ("Lorenzo's oil") as treatment for adrenomyeloneuropathy.
P Aubourg et al.
The New England journal of medicine, 329(11), 745-752 (1993-09-09)
Adrenomyeloneuropathy is an X-linked recessive disorder characterized by myelopathy, peripheral neuropathy, and cerebral demyelination, which develop in association with the accumulation of very-long-chain fatty acids. The administration of oleic and erucic acids inhibits the synthesis of very-long-chain fatty acids. Recently
Hugo W Moser et al.
Archives of neurology, 62(7), 1073-1080 (2005-07-13)
To identify asymptomatic boys with X-linked adrenoleukodystrophy who have a normal magnetic resonance image (MRI), and to assess the effect of 4:1 glyceryl trioleate-glyceryl trierucate (Lorenzo's oil) on disease progression. Eighty-nine boys (mean +/- SD baseline age, 4.7 +/- 4.1
Marc Engelen et al.
Journal of inherited metabolic disease, 35(6), 1137-1145 (2012-03-27)
X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ABCD1 gene encoding ALDP, an ATP-binding-cassette (ABC) transporter located in the peroxisomal membrane. ALDP deficiency results in impaired peroxisomal β-oxidation and the subsequent accumulation of very long-chain fatty acids (VLCFA; >
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