719919
Resomer® RG 752 H, Poly(D,L-lactide-co-glycolide)
acid terminated, lactide:glycolide 75:25, Mw 4,000-15,000
Synonym(s):
PLGA
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About This Item
Linear Formula:
[C3H4O2]x[C2H2O2]y
CAS Number:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.23
SMILES string
O2C(C(=O)OC(C2=O)C)C.O1CC(=O)OCC1=O
InChI
1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2
InChI key
LCSKNASZPVZHEG-UHFFFAOYSA-N
form
(Powder or Solid or Chunk(s))
feed ratio
lactide:glycolide 75:25
mol wt
Mw 4,000-15,000
degradation timeframe
<6 months
impurities
≤0.1% Sulfated Ash (CONF0010 Conforms)
viscosity
0.14-0.22 dL/g, 0.5 % in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)
transition temp
Tg 42-46 °C
storage temp.
2-8°C
Quality Level
Related Categories
General description
Poly(D,L-lactide-co-glycolide) (PLGA) is a biodegradable andbioabsorbable polymer that is widely used in the formulation of implantable andinjectable drug delivery systems. PLGA material induces minimal inflammatoryresponse inside the body and degrades to produce biocompatible lactic andglycolic acids.
Legal Information
Product of Evonik
RESOMER is a registered trademark of Evonik Rohm GmbH
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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International journal of nanomedicine, 7, 5501-5516 (2012-10-25)
Resveratrol, like other natural polyphenols, is an extremely photosensitive compound with low chemical stability, which limits the therapeutic application of its beneficial effects. The development of innovative formulation strategies, able to overcome physicochemical and pharmacokinetic limitations of this compound, may
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Current development efforts of subunit vaccines against Toxoplasma gondii, the etiological agent of toxoplasmosis, have been focused mainly on tachyzoite surface antigen 1 (SAG1). Since microparticles made from poly (lactide-co-glycolide) (PLG) polymers have been developed as safe, potent adjuvants or
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