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Merck

732621

Poly(ethylene glycol) methyl ether

average MN 10,000, methoxy, hydroxyl

Synonym(s):

Polyethylene glycol, Methoxy poly(ethylene glycol), Polyethylene glycol monomethyl ether, mPEG

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About This Item

Linear Formula:
CH3(OCH2CH2)nOH
CAS Number:
9004-74-4
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:
MFCD00084416

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Product Name

Poly(ethylene glycol) methyl ether, average Mn 10,000

SMILES string

O(CCO)C

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

InChI key

XNWFRZJHXBZDAG-UHFFFAOYSA-N

vapor density

>1 (vs air)

vapor pressure

0.05 mmHg ( 20 °C)

form

chunks, powder or crystals

mol wt

average Mn 10,000

mp

60-65 °C

Mw/Mn

≤1.2

Ω-end

hydroxyl

α-end

methoxy

storage temp.

−20°C

Quality Level

100

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

415.0 °F - closed cup

flash_point_c

212.80 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV0350
MKCQ4532
MKCM1715
MKCH8723
MKCH0444

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Yiyi Yu et al.
Journal of pharmaceutical sciences, 102(3), 1054-1062 (2013-01-03)
To promote the application of methoxy poly(ethylene glycol)-cholesterol (mPEG-Chol), mPEG-Chol was used to prepare core-shell micelles encapsulating poorly water-soluble docetaxel (DTX-PM) by modified cosolvent evaporation method. Approaches to enhance DTX entrapment efficiency (EE) and minimize particle size were investigated in
Pengxiang Zhao et al.
Chemical communications (Cambridge, England), 49(31), 3218-3220 (2013-03-14)
"Click" chemistry now offers access to a great variety of triazoles, and the first example of a strategy to stabilize gold nanoparticles (AuNPs) with a new 1,2,3-triazole-mPEG ligand is developed here together with preliminary examples of possible applications.
Mulu Z Tesfay et al.
Journal of virology, 87(7), 3752-3759 (2013-01-18)
We are developing oncolytic vesicular stomatitis viruses (VSVs) for systemic treatment of multiple myeloma, an incurable malignancy of antibody-secreting plasma cells that are specifically localized in the bone marrow. One of the presumed advantages for using VSV as an oncolytic
Hyo Won Seo et al.
Biomaterials, 34(11), 2748-2757 (2013-01-25)
The effectiveness of systemically administered anticancer treatments is limited by difficulties in achieving therapeutic doses within tumors, a problem that is complicated by dose-limiting side effects to normal tissue. To increase the efficacy and reduce the toxicity of systemically administered
Yanjie Bao et al.
Pharmaceutical research, 30(2), 342-351 (2012-09-18)
To determine the influence of physicochemical properties of lipid nanoparticles (LNPs) carrying siRNA on their gene silencing in vivo. Mechanistic understanding of how the architecture of the nanoparticle can alter gene expression has also been studied. The effect of 3-N-[(ω-methoxypoly(ethylene
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