901575
t-Boc-N-amido-PEG3-CH2CO2H
≥95%
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About This Item
Empirical Formula (Hill Notation):
C13H25NO7
CAS Number:
Molecular Weight:
307.34
UNSPSC Code:
51171641
NACRES:
NA.22
MDL number:
Assay:
≥95%
Form:
liquid
assay
≥95%
form
liquid
reaction suitability
reagent type: linker
functional group
Boc, amine, carboxylic acid
storage temp.
−20°C
SMILES string
OC(COCCOCCOCCNC(OC(C)(C)C)=O)=O
InChI
1S/C13H25NO7/c1-13(2,3)21-12(17)10(14)8-19-6-4-18-5-7-20-9-11(15)16/h10H,4-9,14H2,1-3H3,(H,15,16)
InChI key
FUUVHHQEYXVKFA-UHFFFAOYSA-N
Application
This is a crosslinker with a t-Boc protected amine on one end and a carboxyl group on the other end. The compound contains three PEG units to help improve solubility.
t-Boc-N-amido-PEG3-CH2CO2H is a heterobifunctional, PEGylated crosslinker featuring a Boc-protected amine at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. t-Boc-N-amido-PEG3-CH2CO2H can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
Legal Information
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
Storage Class
10 - Combustible liquids
wgk
WGK 3
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