901579
t-Boc-N-amido-PEG1-CH2CO2H
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About This Item
Empirical Formula (Hill Notation):
C9H17NO5
CAS Number:
Molecular Weight:
219.23
UNSPSC Code:
51171641
NACRES:
NA.22
MDL number:
Form:
liquid
form
liquid
reaction suitability
reagent type: cross-linking reagent
functional group
Boc, amine, carboxylic acid
storage temp.
−20°C
SMILES string
O=C(O)COCCNC(OC(C)(C)C)=O
InChI
1S/C9H17NO5/c1-9(2,3)15-8(13)10-4-5-14-6-7(11)12/h4-6H2,1-3H3,(H,10,13)(H,11,12)
InChI key
UPBQMAHYLWJGDW-UHFFFAOYSA-N
Application
This is a crosslinker with a t-Boc protected amine on one end and a carboxyl group on the other end. The compound contains a single PEG unit to help improve solubility
t-Boc-N-amido-PEG1-CH2CO2H is a heterobifunctional, PEGylated crosslinker featuring a Boc-protected amine at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. t-Boc-N-amido-PEG1-CH2CO2H can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
Legal Information
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
Storage Class
10 - Combustible liquids
wgk
WGK 3
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