H20806
4-Hydroxybenzyl alcohol
99%
Synonym(s):
NSC 227926
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About This Item
Linear Formula:
HOC6H4CH2OH
CAS Number:
Molecular Weight:
124.14
UNSPSC Code:
12164502
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-768-0
Beilstein/REAXYS Number:
1858967
MDL number:
Assay:
99%
Form:
powder or crystals
InChI key
BVJSUAQZOZWCKN-UHFFFAOYSA-N
InChI
1S/C7H8O2/c8-5-6-1-3-7(9)4-2-6/h1-4,8-9H,5H2
SMILES string
OCc1ccc(O)cc1
assay
99%
form
powder or crystals
reaction suitability
reagent type: cross-linking reagent
Quality Level
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General description
4-Hydroxybenzyl alcohol (HBA) is a phenolic compound found in Gastrodia elata. It is an antioxidant and anti-asthmatic agent.HBA can also be used as a precursor to synthesize hydrogen peroxide-responsive copolyoxalate nanoparticles and polymers.
Application
4-Hydroxybenzyl alcohol can be used as a precursor for the synthesis of:
- HBA-incorporated copolyoxalate (HPOX) nanoparticles as potential drug delivery system.
- Poly(4-hydroxybenzyl alcohol) by enzyme catalyzed reaction.
- 4-Hydroxybenzyl imidazole derivatives.
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 3 - Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Enzyme mediated oxidative polymerization of 4-hydroxybenzyl alcohol for optical applications.
Kumar V, et al.
Journal of Macromolecular Science, Part A: Pure and Applied Chemistry, 39(10), 1183-1193 (2002)
Synthesis and biochemical evaluation of a range of sulfonated derivatives of 4-hydroxybenzyl imidazole as highly potent inhibitors of rat testicular 17α-hydroxylase/17, 20-lyase (P-45017α).
Ahmed S, et al.
Bioorganic & Medicinal Chemistry Letters, 19(16), 4698-4701 (2009)
Hydrogen peroxide-responsive copolyoxalate nanoparticles for detection and therapy of ischemia-reperfusion injury
D Lee, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 172, 1102-1110 (2013)
M W Laschke et al.
British journal of pharmacology, 163(4), 835-844 (2011-03-04)
4-Hydroxybenzyl alcohol (HBA) is a phenolic plant compound, which has been shown to influence many cellular mechanisms. In the present study, we analysed in vitro and in vivo the anti-angiogenic actions of this pleiotropic agent. Migration and protein expression of
Shan-Shan Yu et al.
Brain research, 1308, 167-175 (2009-10-28)
4-hydroxybenzyl alcohol (4-HBA), one of the major active phenolic constituents of Gastrodia elata Blume, a very important traditional Chinese medicinal herb, has been shown to be an effective agent against the central and peripheral nervous disorders. In this study, we
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