M1626
6-Methoxyharmalan
crystalline
Synonym(s):
4,9-Dihydro-6-methoxy-1-methyl-3H-pyrido(3,4-b)indole
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About This Item
Empirical Formula (Hill Notation):
C13H14N2O
CAS Number:
Molecular Weight:
214.26
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Product Name
6-Methoxyharmalan, crystalline
InChI
1S/C13H14N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7,15H,5-6H2,1-2H3
SMILES string
COc1ccc2[nH]c3C(C)=NCCc3c2c1
InChI key
HMBHRMFLDKKSCT-UHFFFAOYSA-N
form
crystalline
color
yellow
storage temp.
2-8°C
Quality Level
Gene Information
Application
- Reactant for preparation of TRPV1-dependent vasodilator
Biochem/physiol Actions
Weak serotonin inhibitor
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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V P Poshivalov
Biulleten' eksperimental'noi biologii i meditsiny, 99(3), 323-325 (1985-03-01)
The ethological spectrum of four beta-carbolines was studied for intraspecific aggression, sociability integration and individual behavior. It was established that beta-carboline-3-carboxyethyl ether given at subconvulsant doses increases aggression, lowers sociability as a diazepam antagonist. Diazepam reduces aggression and increases sociability.
Fernando D Villarruel et al.
Physical chemistry chemical physics : PCCP, 22(36), 20901-20913 (2020-09-12)
3,4-Dihydro-β-carbolines (DHβCs) are a set of endogenously synthesized alkaloids spread over a great variety of living species (e.g., plants, animals and microorganisms), playing a broad spectrum of biological, biochemical and/or pharmacological roles, in a structure-dependent manner. Addressing unresolved fundamental aspects
Sudeep Karki et al.
Analytical biochemistry, 587, 113463-113463 (2019-10-02)
Synaptic adhesion molecules, including presynaptic neurexins (NRXNs) and post-synaptic leucine-rich repeat transmembrane (LRRTM) proteins are important for development and maintenance of brain neuronal networks. NRXNs are probably the best characterized synaptic adhesion molecules, and one of the major presynaptic organizer
M Micaela Gonzalez et al.
International journal of antimicrobial agents, 52(4), 459-468 (2018-07-15)
Several commercial and novel synthetic β-carbolines (βCs) were evaluated for their antiviral activity against herpes simplex virus type 1 (HSV-1) using an adapted MTS assay. Of 21 drugs tested, although 11 exerted antiviral activity at non-cytotoxic concentrations, only 3 of
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