N27209
4-Nitrothiophenol
technical grade, 80%
Synonym(s):
p-Nitrophenyl mercaptan, pNTP, 4-Nitrobenzenethiol
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About This Item
Linear Formula:
O2NC6H4SH
CAS Number:
Molecular Weight:
155.17
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
217-436-4
Beilstein/REAXYS Number:
606924
MDL number:
Assay:
80%
Form:
solid
InChI key
AXBVSRMHOPMXBA-UHFFFAOYSA-N
InChI
1S/C6H5NO2S/c8-7(9)5-1-3-6(10)4-2-5/h1-4,10H
SMILES string
[O-][N+](=O)c1ccc(S)cc1
grade
technical grade
assay
80%
form
solid
mp
72-77 °C (lit.)
storage temp.
2-8°C
Quality Level
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Related Categories
Application
4-Nitrothiophenol has been used in the synthesis of dual emission fluorescent probe for the differential sensing of of glutathione (GSH) and cysteine/homocysteine (Cys/Hcy). pNTP can also be used to synthesize diaryl thioethers via copper-catalyzed C-S coupling reaction.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Camiel H van Hoorn et al.
Applied spectroscopy, 71(7), 1551-1559 (2017-07-01)
A fast high-resolution screening method for reactive surfaces is presented. Atomic force microscopy (AFM) and surface-enhanced Raman spectroscopy (SERS) are combined in one method in order to be able to obtain both morphological and chemical information about processes at a
M Yamamoto et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 24(3), 247-250 (1986-03-01)
A simple and sensitive method for the determination of N-nitrosomethylurea (NMU) in biological fluids was developed. The principle is based on the formation of 4-nitrothiophenol methyl thioether (NTP-Me) from 4-nitrothiophenol (NTP) and diazomethane formed from MNU by adding alkali. After
B O Skadtchenko et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 57A(5), 1009-1016 (2001-05-26)
The interpretation of the surface-enhanced Raman scattering (SERS) spectra of p-nitrothiophenol (p-NTP) is reported. SERS spectra were obtained by vacuum evaporation and casting of p-NTP onto silver island films, and also from colloidal silver solutions. The vibrational spectra of the
Ze-Yuan Dong et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 12(13), 3575-3579 (2006-02-24)
To elucidate the relationships between molecular recognition and catalytic ability, we chose three assay systems using three different thiol substrates, glutathione (GSH), 3-carboxyl-4-nitrobenzenethiol (CNBSH), and 4-nitrobenzenethiol (NBSH), to investigate the glutathione peroxidase (GPx) activities of 2,2'-ditellurobis(2-deoxy-beta-cyclodextrin) (2-TeCD) in the presence
Qiaofeng Yao et al.
Nature communications, 8(1), 1555-1555 (2017-11-18)
Precise control of alloying sites has long been a challenging pursuit, yet little has been achieved for the atomic-level manipulation of metallic nanomaterials. Here we describe utilization of a surface motif exchange (SME) reaction to selectively replace the surface motifs
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