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About This Item
Empirical Formula (Hill Notation):
C42H85NO5
CAS Number:
Molecular Weight:
684.13
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
N-24:0(2R-OH) Phytosphingosine, Avanti Research™ - A Croda Brand 860924P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (860924P-10mg), pkg of 1 × 5 mg (860924P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860924P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
O[C@]([H])(CCCCCCCCCCCCCC)[C@](O)([H])[C@@]([H])(NC([C@H](O)CCCCCCCCCCCCCCCCCCCCCC)=O)CO
InChI
1S/C42H85NO5/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-40(46)42(48)43-38(37-44)41(47)39(45)35-33-31-29-27-25-16-14-12-10-8-6-4-2/h38-41,44-47H,3-37H2,1-2H3,(H,43,48)
InChI key
ZFUXWVVVWGWGPQ-UHFFFAOYSA-N
General description
N-24:0(2R-OH) Phytosphingosine, also called as N-(2′-(R)-hydroxylignoceroyl)-phytosphingosine, is a sphingolipid that belongs to the group of phytoceramides. Phytosphingosine is a sphingoid base with hydroxyl group at the C4 position. It is highly found in plants and fungi. In addition, phytosphingosine is also present in mammalian epidermis, including the stratum corneum.
Application
N-24:0(2R-OH) Phytosphingosine, also called as N-(2′-(R)-hydroxylignoceroyl)-phytosphingosine may be used to study its effects in different hybrids of Zea mays.
Biochem/physiol Actions
Phytosphingosine and its derivatives play a vital role in the body′s natural defense system. These lipids prevent dehydration of skin, control epidermal cell growth, differentiation and apoptosis. Phytosphingosine also exhibits anti-bactericidal and anti-inflammatory properties.
Packaging
5 mL Amber Glass Screw Cap Vial (860924P-10mg)
5 mL Amber Glass Screw Cap Vial (860924P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
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Paola Giorni et al.
Toxins, 7(9), 3657-3670 (2015-09-18)
Lipid molecules are increasingly recognized as signals exchanged by organisms interacting in pathogenic and/or symbiotic ways. Some classes of lipids actively determine the fate of the interactions. Host cuticle/cell wall/membrane components such as sphingolipids and oxylipins may contribute to determining
Chiara Mencarelli et al.
Cellular and molecular life sciences : CMLS, 70(2), 181-203 (2012-06-26)
Ceramide, the precursor of all complex sphingolipids, is a potent signaling molecule that mediates key events of cellular pathophysiology. In the nervous system, the sphingolipid metabolism has an important impact. Neurons are polarized cells and their normal functions, such as
Byung-Hak Kim et al.
The Journal of investigative dermatology, 134(4), 1023-1032 (2013-11-02)
Phytosphingosine is abundant in plants and fungi and is found in mammalian epidermis, including the stratum corneum. Phytosphingosine and its derivatives N-acetyl phytosphingosine and tetraacetyl phytosphingosine are part of the natural defense system of the body. However, these molecules exhibit