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Merck

LM1601

Avanti

17:1 Lyso PC

Avanti Research™ - A Croda Brand

Synonym(s):

1-(10Z-heptadecenoyl)-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C25H50NO7P
CAS Number:
1246304-62-0
Molecular Weight:
507.64
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

17:1 Lyso PC, Avanti Research™ - A Croda Brand LM1601, methanol solution

InChI key

XBGIMYLOTRDXPK-AGXIJRPPSA-N

SMILES string

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCC/C=C\CCCCCC)=O

assay

>99% (TLC)

form

methanol solution

packaging

pkg of 1 × 1 mL (LM1601-1EA)

manufacturer/tradename

Avanti Research™ - A Croda Brand LM1601

concentration

~10 μg/mL (Refer to C of A for lot specific concentration. )

shipped in

dry ice

storage temp.

−20°C

General description

Lysophosphatidylcholine (LPC) is a polar lipid, localized to the cell membranes of oxidized lipoproteins.

Application

17:1 Lyso PC has been used as an LIPID MAPS internal standard for lipid extraction from serum and quantification in liquid chromatography mass-spectrometry (LC-MS) analysis.

Biochem/physiol Actions

Lysophosphatidylcholine (LPC) is a bioactive molecule involved in various biological processes such as vascular reproduction, development and myelination. It is associated to the progression of atherosclerosis, with findings of high concentration of LPC in the lesions/plaques. Higher levels of LPC are also found in oxidatively damaged low-density lipoprotein (oxLDL) indicating cardiovascular disease. LPC is known to be implicated in neuronal diseases and cancer.

Packaging

2 mL Amber Glass Sealed Ampule (LM1601-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

67-56-1

CAS No.

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Certificates of Analysis (COA)

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Victoria Meslier et al.
Gut (2020-02-23)
This study aimed to explore the effects of an isocaloric Mediterranean diet (MD) intervention on metabolic health, gut microbiome and systemic metabolome in subjects with lifestyle risk factors for metabolic disease. Eighty-two healthy overweight and obese subjects with a habitually
Judith Simcox et al.
Cell metabolism, 26(3), 509-522 (2017-09-07)
Cold-induced thermogenesis is an energy-demanding process that protects endotherms against a reduction in ambient temperature. Using non-targeted liquid chromatography-mass spectrometry-based lipidomics, we identified elevated levels of plasma acylcarnitines in response to the cold. We found that the liver undergoes a
A comprehensive method for lipid profiling by liquid chromatography-ion cyclotron resonance mass spectrometry
Fauland A, et al.
Journal of Lipid Research, 52(12), 2314-2322 (2011)
Alexander Fauland et al.
Journal of lipid research, 52(12), 2314-2322 (2011-10-01)
This work aims to combine chromatographic retention, high mass resolution and accuracy, MS/MS spectra, and a package for automated identification and quantitation of lipid species in one platform for lipidomic analysis. The instrumental setup elaborated comprises reversed-phase HPLC coupled to

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