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Merck

34998-M

Acetonitrile

≥99.9%, HPLC Plus, suitable for HPLC

Synonym(s):

ACN, Cyanomethane, Ethyl nitrile, Methyl cyanide

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About This Item

Linear Formula:
CH3CN
CAS Number:
75-05-8
Molecular Weight:
41.05
NACRES:
NA.21
PubChem Substance ID:
329755104
eCl@ss:
39031501
UNSPSC Code:
12190000
EC Number:
200-835-2
MDL number:
MFCD00001878
Beilstein/REAXYS Number:
741857
Grade:
HPLC Plus
Assay:
≥99.9%
Technique(s):
HPLC: suitable
Bp:
81-82 °C (lit.)
Vapor pressure:
72.8 mmHg ( 20 °C)

Key Documents

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Product Name

Acetonitrile, HPLC Plus, ≥99.9%

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N

InChI

1S/C2H3N/c1-2-3/h1H3

SMILES string

CC#N

grade

HPLC Plus

vapor density

1.41 (vs air)

vapor pressure

72.8 mmHg ( 20 °C)

assay

≥99.9%

form

liquid

autoignition temp.

973 °F

expl. lim.

16 %

baseline drift measuring range

≤12 mAU (210 nm)

technique(s)

HPLC: suitable

impurities

≤0.0001% free alkali (as NH3)
≤0.0002% non-volatile matter
≤0.001% free acid (as CH3COOH)
≤0.01% water (Karl Fischer)
≤0.5 ppb fluorescence (quinine) at 254 nm
≤0.5 ppb fluorescence (quinine) at 365 nm

halogenated residue

10 ng/L (as heptachlor epoxide)

refractive index

n20/D 1.344 (lit.)

bp

81-82 °C (lit.)

mp

−45 °C (lit.)

density

0.786 g/mL at 25 °C (lit.)

HPLC-gradient

≤0.2 mAU at 254 nm
≤1 mAU at 210 nm

λ

H2O reference

UV absorption

λ: 195 nm Amax: ≤0.10
λ: 200 nm Amax: ≤0.02
λ: 228 nm Amax: ≤0.005
λ: 235 nm Amax: ≤0.0044
λ: 250 nm Amax: ≤0.0044
λ: 400 nm Amax: ≤0.0044

format

neat

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Application

Acetonitrile has been used to compose the gradient system for the HPLC detection of diphenylmethane diisocyanate, a polymeric degradation product.
New Quality UPLC Plus Acetonitrile is suitable for all applications including:
Mass spectrometry, HPLC, TLC, GPC, UV, IR, GC, Pesticide Residue Analysis, and RNA/DNA Synthesis and Purification.

General description

Acetonitrile (MeCN) is widely employed as a solvent in various studies and has high dielectric constant (37.5). Various purification procedures to obtain different grades of acetonitrile for use in different studies (polarography, spectroscopy, etc.) have been reported by many researchers.

Other Notes

Important notice
This product will be phased out towards early 2019. There is a replacement product available : 34998
Discover LiChropur reagents ideal for HPLC or LC-MS analysis
Pure-Pac® II containers require the Micromatic MacroValve coupler for dispensing solvents, Z560723.

Packaging

View returnable container options.

Preparation Note

Product filtered through a 0.2 μm filter

Legal Information

Pure-Pac is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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H Haugen et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 73(2), 229-237 (2005-03-10)
This article deals with enzyme-induced biodegradation behavior of thermoplastic polyether-urethane (TPU). Porous scaffolds were processed by a new foaming method applied in hot pressing and injection molding. The scaffolds were subsequently gamma sterilized. The samples were incubated with cholesterol esterase

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