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Merck

AP114P

Goat Anti-Human IgM Antibody, Fc5µ, HRP conjugate

Chemicon®, from goat

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
eCl@ss:
32160702
Conjugate:
peroxidase conjugate
Clone:
polyclonal
Application:
ELISA
western blot
Species reactivity:
human
Citations:
10
Technique(s):
ELISA: suitable
western blot: suitable
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Product Name

Goat Anti-Human IgM Antibody, Fc5µ, HRP conjugate, Chemicon®, from goat

biological source

goat

conjugate

peroxidase conjugate

antibody form

affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
western blot: suitable

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Application

EIA: 1:5,000-1:100,000.
Western blots: 1:5,000-1:200,000.
Immunohistochemistry: 1:500-1:5,000.

Optimal working dilutions must be determined by the end user.
Goat anti-Human IgM Antibody, Fc5μ, HRP conjugate is an antibody against Human IgM for use in ELISA & WB.
Research Category
Secondary & Control Antibodies
Research Sub Category
Fragment Specific Secondary Antibodies

Biochem/physiol Actions

Based on immunoelectrophoresis, the antibody reacts with the Fc5μ portion of the human IgM heavy chain. Does not react with human IgG or IgA, or with the light chains of human immunoglobulins. No reactivity against non-immunoglobulin serum proteins, but the antibody may cross-react with IgM from other species.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

IgM constitutes about 10% of serum immunoglobulins. IgM is prominent in early immune responses to most antigens and predominates in certain antibody responses such as ′natural′ blood group antibodies. IgM (with IgD) is the major immunoglobulin expressed on the surface of B cells.

Immunogen

Prepared from purified human IgM Fc5μ fragment.

Physical form

0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6 with 15mg/mL BSA. Contains no preservative. Lyophilized.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lin Sun et al.
Frontiers in bioengineering and biotechnology, 11, 1320586-1320586 (2023-12-21)
Plants are being increasingly recognized for the production of complex human proteins, including monoclonal antibodies (mAbs). Various methods have been applied to boost recombinant expression, with DNA codon usage being an important approach. Here, we transiently expressed three complex human
Krasimir Kostov et al.
Diagnostics (Basel, Switzerland), 11(5) (2021-06-03)
Thickening of the vascular basement membrane (BM) is a fundamental structural change in the small blood vessels in diabetes. Collagen type IV (CIV) is a major component of the BMs, and monitoring the turnover of this protein in type 2
Krasimir Kostov et al.
Medicina (Kaunas, Lithuania), 56(5) (2020-05-15)
Background and objectives: HbA1c measurements may be useful not only in optimizing glycemic control but also as a tool for managing overall vascular risk in patients with diabetes. In the present study, we investigate the clinical significance of HbA1c as
Juan Rivera-Correa et al.
eLife, 8 (2019-11-13)
Anemia is a common complication of malaria that is characterized by the loss of infected and uninfected erythrocytes. In mouse malaria models, clearance of uninfected erythrocytes is promoted by autoimmune anti-phosphatidylserine (PS) antibodies produced by T-bet+B-cells, which bind to exposed
Cleopatra K Mugyenyi et al.
PloS one, 8(7), e68304-e68304 (2013-07-19)
Antibodies to P. falciparum apical membrane protein 1 (AMA1) may contribute to protective immunity against clinical malaria by inhibiting blood stage growth of P. falciparum, and AMA1 is a leading malaria vaccine candidate. Currently, there is limited knowledge of the

Global Trade Item Number

SKUGTIN
AP114P08436037123023

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