Milli-Mark^®Anti-Cytokeratin 5 Antibody, 6-FITC, clone D5/16B4

The calculated for Cytokeratin is 62 kDa, however, different isoforms state Cytokeratin 4 (59 kDa), Cytokeratin 5 (58 kDa) and Cytokeratin 6 (56 kDa).

The cytokeratins are a family of intermediate filaments found in almost all epithelial cells. They are divided into four subclasses depending on their patterns of reactivity and electrophoretic characteristics and are also arranged I a numbered series of 20 or more acoring to molecular weight and isoelectric point (Quinlan et al. 1985). Types 5 and 6 of cytokeratin (CK5/6) are in high frequency in mesothelial cells, as opposed to cells of adenocarcinoma. CK5/6 has been shown to be a reliable marker for mesothelioma and squamous cell carcinoma of the lung and Bowen′s disease. It does not react with pulmonary adenocarcinoma.

Purified cytokeratin 5 (Wild, 1986) (Mischke, 1987).

Milli-MarkAnti-Cytokeratin 5 Antibody, 6-FITC, clone D5/16B4 is an antibody against Cytokeratin 5 for use in FC.

Research Category
Cell Structure

Research Sub Category
Cytoskeleton

Antibody recognizes Human Cytokeratin.

Protein A purified

Purified mouse monoclonal IgG1 conjugated to FITC in PBS buffer with 15mg/mL BSA and sodium azide at 0.1%.

Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt.

Control
A431 cells

Evaluated by flow cytometry using A431 cells

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