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Merck

72511

Luteolin

analytical standard

Synonym(s):

3′,4′,5,7-Tetrahydroxyflavone

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About This Item

Empirical Formula (Hill Notation):
C15H10O6
CAS Number:
491-70-3
Molecular Weight:
286.24
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
329764132
EC Number:
207-741-0
Beilstein/REAXYS Number:
292084
MDL number:
MFCD00017309

Key Documents

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InChI

1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H

SMILES string

Oc1cc(O)c2C(=O)C=C(Oc2c1)c3ccc(O)c(O)c3

InChI key

IQPNAANSBPBGFQ-UHFFFAOYSA-N

grade

analytical standard

assay

≥97.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

~330 °C (lit.)

application(s)

food and beverages

format

neat

storage temp.

2-8°C

Quality Level

100

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General description

Luteolin is a naturally occurring flavone, readily present in vegetables. It may possess many biological properties like anti-tumor activity against condition of skin papilloma.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

This compound is commonly found in plants of the genus: achillea

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP1730
BCCL7024
BCCK3172
BCCH8513
BCCG7743

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Application of luteolin nanomicelles anti-glioma effect with improvement in vitro and in vivo
Zheng S, et al.
Oncotarget, 8(37) (2017)
Bonavida B
Sensitization of Cancer Cells for Chemo/Immuno/Radio-therapy (2008)
Dietary luteolin attenuates chronic liver injury induced by mercuric chloride via the Nrf2/NF-?B/P53 signaling pathway in rats
Zhang H, et al.
Oncotarget, 8(25) (2017)
Miguel López-Lázaro
Mini reviews in medicinal chemistry, 9(1), 31-59 (2009-01-20)
Epidemiological evidence suggests that flavonoids may play an important role in the decreased risk of chronic diseases associated with a diet rich in plant-derived foods. Flavonoids are also common constituents of plants used in traditional medicine to treat a wide
Leticia Correa Manjolin et al.
Food chemistry, 141(3), 2253-2262 (2013-07-23)
Fisetin, quercetin, luteolin and 7,8-hydroxyflavone show high activity in Leishmania cultures and present low toxicity to mammalian cells. In this work, the structural aspects of 13 flavonoids were analyzed for their inhibition of the arginase enzyme from Leishmania (Leishmania) amazonensis.
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