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Merck

93535

N-(Propionyloxy)succinimide

for LC-MS derivatization, LiChropur™, ≥95% (HPLC)

Synonym(s):

1-(1-Oxopropoxy)-2,5-pyrrolidinedione, 2,5-Dioxopyrrolidin-1-yl-propanoate, Propanoic acid-NHS ester, Propionyl-Osu, Succinimidyl propionate

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About This Item

Empirical Formula (Hill Notation):
C7H9NO4
CAS Number:
30364-55-7
Molecular Weight:
171.15
UNSPSC Code:
41116105
NACRES:
NA.22
MDL number:
MFCD03427483

Key Documents

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Product Name

N-(Propionyloxy)succinimide, for LC-MS derivatization, LiChropur™, ≥95% (HPLC)

InChI

1S/C7H9NO4/c1-2-7(11)12-8-5(9)3-4-6(8)10/h2-4H2,1H3

SMILES string

O=C(CCC1=O)N1OC(CC)=O

InChI key

AASBXERNXVFUEJ-UHFFFAOYSA-N

assay

≥95% (HPLC)

form

solid

quality

LiChropur™
for LC-MS derivatization

reaction suitability

reagent type: derivatization reagent
reaction type: Acylations

technique(s)

LC/MS: suitable

Quality Level

100

Related Categories

General description

N-(Propionyloxy)succinimide is commonly used as a mobile phase additive in liquid chromatography-mass spectrometry (LC-MS) and its typical application involves the derivatization of histones. It involves the following properties:        
  • Extensive QC testing ensures the highest specifications.        
  • Optimized to improve ionization and resolution.        
  • Extremely low levels of inorganic and organic impurities.        
  • Manufactured specifically for accurate and fast LC-MS.

Other Notes

Discover LiChropur™ reagents ideal for HPLC or LC-MS analysis

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN7832
BCCL7008
BCCK1473
BCCF6455
BCCC9300

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Masaru Fujimoto et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(40), 25150-25158 (2020-09-25)
The plasma membrane (PM) acts as the interface between intra- and extracellular environments and exhibits a tightly regulated molecular composition. The composition and amount of PM proteins are regulated by balancing endocytic and exocytic trafficking in a cargo-specific manner, according
Yea Lu Tay et al.
Scientific reports, 9(1), 19757-19757 (2019-12-26)
Mitragyna speciosa Korth (M. speciosa) has been widely used as a recreational product, however, there are growing concerns on the abuse potentials and toxicity of the plant. Several poisoning and fatal cases involving kratom and mitragynine have been reported but
Somasekhar R Chinnadayyala et al.
Sensors (Basel, Switzerland), 19(24) (2020-01-01)
An electrochemical capacitance immunosensor based on an interdigitated wave-shaped micro electrode array (IDWµE) for direct and label-free detection of C-reactive protein (CRP) was reported. A self-assembled monolayer (SAM) of dithiobis (succinimidyl propionate) (DTSP) was used to modify the electrode array
Adriana Ordóñez et al.
Cell reports, 35(7), 109144-109144 (2021-05-20)
Circulating polymers of α1-antitrypsin (α1AT) are neutrophil chemo-attractants and contribute to inflammation, yet cellular factors affecting their secretion remain obscure. We report on a genome-wide CRISPR-Cas9 screen for genes affecting trafficking of polymerogenic α1ATH334D. A CRISPR enrichment approach based on
Anne Sigaard Bie et al.
Cell stress & chaperones, 25(3), 407-416 (2020-02-16)
The HSP60/HSP10 chaperonin assists folding of proteins in the mitochondrial matrix space by enclosing them in its central cavity. The chaperonin forms part of the mitochondrial protein quality control system. It is essential for cellular survival and mutations in its
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