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Merck

96353

Kaempferol

analytical standard

Synonym(s):

3,4′,5,7-Tetrahydroxyflavone, 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, Robigenin

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About This Item

Empirical Formula (Hill Notation):
C15H10O6
CAS Number:
520-18-3
Molecular Weight:
286.24
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
329770498
EC Number:
208-287-6
Beilstein/REAXYS Number:
304401
MDL number:
MFCD00016938

Key Documents

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Product Name

Kaempferol, analytical standard

InChI

1S/C15H10O6/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,16-18,20H

InChI key

IYRMWMYZSQPJKC-UHFFFAOYSA-N

SMILES string

Oc1ccc(cc1)C2=C(O)C(=O)c3c(O)cc(O)cc3O2

grade

analytical standard

assay

≥99.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

Quality Level

100

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Related Categories

Application

Chromogenic reagent for antimony in the low ppm range and for gallium and indium in the sub-ppm range.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Potent inhibitor of osteoclastic bone resorption. The effect is believed to be attributable to both the antioxidant and estrogenic activities of kaempferol.

General description

Kaempferol is a bioflavonoid and a main component of the extract of Ginkgo biloba. It is also present in a variety of fruits and vegetables. It may serve as a potent candidate in the treatment of postmenopausal bone loss.

Other Notes

This compound is commonly found in plants of the genus: allium cinnamomum crataegus echinacea eucalyptus ginkgo glycyrrhiza hypericum lycium pimpinella primula sambucus

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM9040
BCCL8463
BCCK7289
BCCJ4507
BCCH3253

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Drugs?Advances in Research and Application: 2012 Edition (2012)
Connective Tissue Cells: Advances in Research and Application: 2011 Edition (2012)
Avinash Kumar et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 82(3), 508-517 (2012-08-29)
A prototype formulation based on layer-by-layer (LbL) nano-matrix was developed to increase bioavailability of kaempferol with improved retention in bone marrow to achieve enhanced bone formation. The layer-by-layer nano-matrix was prepared by sequential adsorption of biocompatible polyelectrolytes over the preformed
A Gohlke et al.
Journal of dairy science, 96(4), 2303-2313 (2013-02-14)
Because of their health-promoting properties, flavonoids are used in feed supplements for ruminants, although scientific evidence for their efficacy in vivo is limited. It has been shown recently that bioavailability of quercetin is low after ruminal administration in cows because
J M Calderón-Montaño et al.
Mini reviews in medicinal chemistry, 11(4), 298-344 (2011-03-25)
Epidemiological studies have revealed that a diet rich in plant-derived foods has a protective effect on human health. Identifying bioactive dietary constituents is an active area of scientific investigation that may lead to new drug discovery. Kaempferol (3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one) is a
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