201154
Sodium fluoride
ACS reagent, ≥99%
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About This Item
Linear Formula:
NaF
CAS Number:
Molecular Weight:
41.99
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352302
EC Number:
231-667-8
MDL number:
Assay:
≥99%
Grade:
ACS reagent
Form:
powder
grade
ACS reagent
Quality Level
agency
suitable for EPA 300
vapor pressure
1.4 mmHg ( 0 °C)
assay
≥99%
form
powder
impurities
≤0.01 meq/g Titr. base, ≤0.02% insolubles, ≤0.03 meq/g Titr. acid, ≤0.1% sodium fluorosilicate
loss
≤0.3% loss on drying
mp
993 °C (lit.)
anion traces
chloride (Cl-): ≤0.005%, sulfate (SO42-): ≤0.03%, sulfite (SO32-): ≤0.005%
cation traces
Fe: ≤0.003%, K: ≤0.02%, heavy metals (as Pb): ≤0.003%
SMILES string
[F-].[Na+]
InChI
1S/FH.Na/h1H;/q;+1/p-1
InChI key
PUZPDOWCWNUUKD-UHFFFAOYSA-M
General description
Sodium fluoride (NaF) is a metallic halide. It has been reported as dental caries preventive agent. It is the most widely employed chemical preservative for the preservation of glucose in blood. It has been reported to stabilize the hepatic microsomal glucose-6-P phosphohydrolase enzyme.
Application
Sodium fluoride may be employed as a fluorination agent in the synthesis of aromatic and aliphatic fluorides. It may be used to prepare the lysis buffer.
Sodium fluoride may be used as a fluorinating agent for chlorine-containing compounds via halogen-exchange reaction.
Starting material for solid state preparation of Na3MnF6 for further high pressure structural determination studies.
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2
supp_hazards
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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The effect on human dental caries of weekly oral rinsing with a sodium fluoride mouthwash: a final report.
Horowitz HS, et al.
Archives of Oral Biology, 16(6), 609-616 (1971)
A prospective, randomized clinical study on the effects of an amine fluoride/stannous fluoride toothpaste/mouthrinse on plaque, gingivitis and initial caries lesion development in orthodontic patients.
?gaard B, et al.
European Journal of Orthodontics, 28(1), 8-12 (2006)
A J Lange et al.
The Journal of biological chemistry, 261(1), 101-107 (1986-01-05)
Stabilization and inhibition of hepatic microsomal glucose-6-P phosphohydrolase (EC 3.1.3.9) by F- requires the presence of Al3+ ions. At millimolar concentrations, reagent grade NaF inhibited glucose-6-P hydrolysis and protected the enzyme against inactivation induced by heat in the presence of