Skip to Content
Merck

M79603

NMP

ReagentPlus®, 99%

Synonym(s):

1-Methyl-2-pyrrolidone, N-Methyl-2-pyrrolidone, NMP

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C5H9NO
CAS Number:
872-50-4
Molecular Weight:
99.13
NACRES:
NA.21
PubChem Substance ID:
329818046
UNSPSC Code:
12352005
EC Number:
212-828-1
MDL number:
MFCD00003193
Beilstein/REAXYS Number:
106420
Assay:
99%
Bp:
202 °C (lit.)
81-82 °C/10 mmHg (lit.)
Vapor pressure:
0.29 mmHg ( 20 °C)
0.99 mmHg ( 40 °C)

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

1-Methyl-2-pyrrolidinone, ReagentPlus®, 99%

SMILES string

CN1CCCC1=O

InChI key

SECXISVLQFMRJM-UHFFFAOYSA-N

InChI

1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3

vapor density

3.4 (vs air)

vapor pressure

0.29 mmHg ( 20 °C)
0.99 mmHg ( 40 °C)

product line

ReagentPlus®

assay

99%

form

liquid

autoignition temp.

518 °F

expl. lim.

9.5 %

dilution

(for general lab use)

impurities

≤0.1% water (Karl Fischer)

color

APHA: ≤50

refractive index

n20/D 1.47 (lit.)

pH

7.7-10.0 (20 °C, 100 g/L)

bp

202 °C (lit.)
81-82 °C/10 mmHg (lit.)

mp

−24 °C (lit.)

density

1.028 g/mL at 25 °C (lit.)

Quality Level

100

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Undergoes condensation reactions with arylthioacetamides and methyl salicylates. Versatile solvent for water miscible applications.

Other Notes

A Greener alternative is available for many NMP applications, Cyrene (807796)

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

195.8 °F - Pensky-Martens closed cup

flash_point_c

91 °C - Pensky-Martens closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

872-50-4

CAS No.

872-50-4

CAS No.

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SHBT1603
SHBS8540
SHBS4797
SHBR6474
SHBR4711

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

U Isele et al.
Journal of pharmaceutical sciences, 83(11), 1608-1616 (1994-11-01)
This work describes the development of an organic solvent dilution method suitable for the large scale manufacturing of small unilamellar liposomes containing the water-insoluble photosensitizer zinc phthalocyanine in the monomeric state. N-Methyl pyrrolidone (NMP)/tert-butyl alcohol was selected as water miscible
The Journal of Organic Chemistry, 58, 7277-7277 (1993)
J. Mol. Catal., 85, L109-L109 (1993)
Journal of the Chemical Society. Chemical Communications, 1437-1437 (1994)
B A Jönsson et al.
Journal of chromatography. B, Biomedical sciences and applications, 694(2), 351-357 (1997-07-04)
A method for simultaneous determination of 5-hydroxy-N-methylpyrrolidone and 2-hydroxy-N-methylsuccinimide in urine is described. These compounds are metabolites of N-methyl-2-pyrrolidone, a powerful and widely used organic solvent. 5-Hydroxy-N-methylpyrrolidone and 2-hydroxy-N-methylsuccinimide were purified from urine by adsorption to a C8 solid-phase extraction
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service